Myelodysplastic Syndromes, Multiple Myeloma, and Other Cancers
Under the CMS-HCC V28 risk adjustment model (PY2026 Medicare Advantage), HCC 19 carries a community non-dual aged RAF of 1.798, and 68 payable ICD-10-CM diagnosis codes map to it. In the V28 hierarchy it is superseded by HCC 17, HCC 18 when a more severe category in the same disease group is also present.
RAF factors
The community factor varies by Medicaid and originally-disabled status; the institutional factor applies to long-term-institutional members. These are the CMS-HCC V28 PY2026 relative factors.
V28 hierarchy
Trumped by: HCC 17, HCC 18 (a more severe category in the same disease group supersedes this one).
Supersedes: HCC 20, HCC 21, HCC 22, HCC 23 (this category is counted instead of these when they co-occur).
ICD-10-CM codes that map to HCC 19 (68)
Payable diagnosis codes that map to this category under CMS-HCC V28 PY2026. Open any code for its full description, HCC mapping, and coding guidance.
- C45.0Mesothelioma of pleura
- C45.1Mesothelioma of peritoneum
- C45.2Mesothelioma of pericardium
- C45.7Mesothelioma of other sites
- C45.9Mesothelioma, unspecified
- C84.40Peripheral T-cell lymphoma, not elsewhere classified, unspecified site
- C84.41Peripheral T-cell lymphoma, not elsewhere classified, lymph nodes of head, face, and neck
- C84.42Peripheral T-cell lymphoma, not elsewhere classified, intrathoracic lymph nodes
- C84.43Peripheral T-cell lymphoma, not elsewhere classified, intra-abdominal lymph nodes
- C84.44Peripheral T-cell lymphoma, not elsewhere classified, lymph nodes of axilla and upper limb
- C84.45Peripheral T-cell lymphoma, not elsewhere classified, lymph nodes of inguinal region and lower limb
- C84.46Peripheral T-cell lymphoma, not elsewhere classified, intrapelvic lymph nodes
- C84.47Peripheral T-cell lymphoma, not elsewhere classified, spleen
- C84.48Peripheral T-cell lymphoma, not elsewhere classified, lymph nodes of multiple sites
- C84.49Peripheral T-cell lymphoma, not elsewhere classified, extranodal and solid organ sites
- C84.4APeripheral T-cell lymphoma, not elsewhere classified, in remission
- C84.70Anaplastic large cell lymphoma, ALK-negative, unspecified site
- C84.71Anaplastic large cell lymphoma, ALK-negative, lymph nodes of head, face, and neck
- C84.72Anaplastic large cell lymphoma, ALK-negative, intrathoracic lymph nodes
- C84.73Anaplastic large cell lymphoma, ALK-negative, intra-abdominal lymph nodes
- C84.74Anaplastic large cell lymphoma, ALK-negative, lymph nodes of axilla and upper limb
- C84.75Anaplastic large cell lymphoma, ALK-negative, lymph nodes of inguinal region and lower limb
- C84.76Anaplastic large cell lymphoma, ALK-negative, intrapelvic lymph nodes
- C84.77Anaplastic large cell lymphoma, ALK-negative, spleen
- C84.78Anaplastic large cell lymphoma, ALK-negative, lymph nodes of multiple sites
- C84.79Anaplastic large cell lymphoma, ALK-negative, extranodal and solid organ sites
- C84.7AAnaplastic large cell lymphoma, ALK-negative, breast
- C84.7BAnaplastic large cell lymphoma, ALK-negative, in remission
- C86.30Subcutaneous panniculitis-like T-cell lymphoma not having achieved remission
- C86.31Subcutaneous panniculitis-like T-cell lymphoma, in remission
- C86.40Blastic NK-cell lymphoma not having achieved remission
- C86.41Blastic NK-cell lymphoma, in remission
- C86.50Angioimmunoblastic T-cell lymphoma not having achieved remission
- C86.51Angioimmunoblastic T-cell lymphoma, in remission
- C90.00Multiple myeloma not having achieved remission
- C90.01Multiple myeloma in remission
- C90.02Multiple myeloma in relapse
- C90.10Plasma cell leukemia not having achieved remission
- C90.11Plasma cell leukemia in remission
- C90.12Plasma cell leukemia in relapse
- C90.20Extramedullary plasmacytoma not having achieved remission
- C90.21Extramedullary plasmacytoma in remission
- C90.22Extramedullary plasmacytoma in relapse
- C90.30Solitary plasmacytoma not having achieved remission
- C90.31Solitary plasmacytoma in remission
- C90.32Solitary plasmacytoma in relapse
- C91.30Prolymphocytic leukemia of B-cell type not having achieved remission
- C91.31Prolymphocytic leukemia of B-cell type, in remission
- C91.32Prolymphocytic leukemia of B-cell type, in relapse
- C91.50Adult T-cell lymphoma/leukemia (HTLV-1-associated) not having achieved remission
- C91.51Adult T-cell lymphoma/leukemia (HTLV-1-associated), in remission
- C91.52Adult T-cell lymphoma/leukemia (HTLV-1-associated), in relapse
- C91.60Prolymphocytic leukemia of T-cell type not having achieved remission
- C91.61Prolymphocytic leukemia of T-cell type, in remission
- C91.62Prolymphocytic leukemia of T-cell type, in relapse
- C94.6Myelodysplastic disease, not elsewhere classified
- D46.0Refractory anemia without ring sideroblasts, so stated
- D46.1Refractory anemia with ring sideroblasts
- D46.20Refractory anemia with excess of blasts, unspecified
- D46.21Refractory anemia with excess of blasts 1
- D46.4Refractory anemia, unspecified
- D46.9Myelodysplastic syndrome, unspecified
- D46.ARefractory cytopenia with multilineage dysplasia
- D46.BRefractory cytopenia with multilineage dysplasia and ring sideroblasts
- D46.CMyelodysplastic syndrome with isolated del(5q) chromosomal abnormality
- D46.ZOther myelodysplastic syndromes
- D47.4Osteomyelofibrosis
- D75.81Myelofibrosis
Frequently asked questions
What is CMS-HCC V28 category 19?
HCC 19 is "Myelodysplastic Syndromes, Multiple Myeloma, and Other Cancers", a payment Hierarchical Condition Category in the CMS-HCC V28 risk adjustment model (100% phase-in for payment year 2026). 68 payable ICD-10-CM codes map to it.
What is the RAF weight for HCC 19?
The community non-dual aged relative factor for CMS-HCC V28 category 19 is 1.798. The exact factor varies by enrollment segment (community Medicaid and originally-disabled status, and institutional); the full segment table is published in the CMS V28 Rate Announcement.
How many ICD-10-CM codes map to HCC 19?
68 payable ICD-10-CM diagnosis codes map to CMS-HCC V28 category 19 (Myelodysplastic Syndromes, Multiple Myeloma, and Other Cancers) for payment year 2026.
Which categories trump HCC 19 in the V28 hierarchy?
HCC 19 is superseded by HCC 17 (Cancer Metastatic to Lung, Liver, Brain, and Other Organs; Acute Myeloid Leukemia Except Promyelocytic), HCC 18 (Cancer Metastatic to Bone, Other and Unspecified Metastatic Cancer; Acute Leukemia Except Myeloid). When a more severe category in the same disease group is documented, it is counted instead of HCC 19.
Source: CMS published ICD-10-CM mapping file plus CMS-HCC v28 PY2026 model software.