C84.7A

Billable

Anaplastic large cell lymphoma, ALK-negative, breast

HCC Category Mapping

V28HCC 19 — Lymphoma and Other Cancers

0.105

V24HCC 10 — Lymphoma and Other Cancers

0.675

ESRDHCC 10 — Lymphoma and Other Cancers

0.000

RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers

0.000

What This Code Means

A type of aggressive lymphoma (cancer of immune cells) that starts in the breast and does not have a specific genetic marker called ALK.

Coding Tips

•Verify the ALK-negative status is documented in the pathology report before assigning this code
•This code is specific to breast involvement; confirm the primary site is the breast and not metastatic disease

Clinical Significance

Anaplastic large cell lymphoma, ALK-negative, involving the breast is a clinically significant code that specifically captures breast implant-associated ALCL (BIA-ALCL) and other breast-based ALCL. BIA-ALCL is a recognized entity associated with textured breast implants and typically presents as a late-onset periprosthetic seroma or mass. Early-stage BIA-ALCL confined to the capsule has excellent prognosis with implant removal, while advanced disease requires systemic therapy.

Documentation Requirements

✓Pathology confirming ALCL with CD30 positivity and ALK-negative status in breast tissue
✓Documentation of breast implant history if applicable
✓Description of presentation (seroma, mass, capsular involvement)
✓Staging of breast involvement (confined to capsule vs. beyond capsule vs. disseminated)
✓Bilateral implant status documented if relevant

Use Additional Code

code to identify:
breast implant status (Z98.82)
personal history of breast implant removal (Z98.86)

Commonly Confused Codes

C50.919 — Malignant neoplasm of breast, unspecified: This is for breast carcinoma, not lymphoma; breast lymphoma requires C84 series codes C84.79 — ALCL ALK-negative, extranodal/solid organ: Use C84.7A specifically when breast is the site; C84.79 is for other extranodal sites C86.6 — Primary cutaneous CD30+ T-cell lymphoproliferative disorder: Skin disease, not breast parenchyma C84.69 — ALCL ALK-positive, extranodal: ALK-positive and not breast-specific; BIA-ALCL is characteristically ALK-negative

Code Hierarchy

└C84Mature T/NK-cell lymphomas └C84.7Anaplastic large cell lymphoma, ALK-negative └C84.7AAnaplastic large cell lymphoma, ALK-negative, breast

└C84.7AAnaplastic large cell lymphoma, ALK-negative, breast