C84.79
BillableAnaplastic large cell lymphoma, ALK-negative, extranodal and solid organ sites
HCC Category Mapping
V28HCC 19 — Lymphoma and Other Cancers
0.105V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers
0.000What This Code Means
A type of aggressive lymphoma (cancer of immune cells) without a specific genetic marker (ALK-negative) that is located outside of lymph nodes, in solid organs or other extranodal sites.
Coding Tips
- •Identify and document the specific extranodal site involved (skin, bone, liver, GI tract, etc.) in the medical record
- •This code is used when the lymphoma primarily affects organs or tissues outside the lymph node system
Clinical Significance
Anaplastic large cell lymphoma, ALK-negative, involving extranodal and solid organ sites represents organ-based disease from aggressive T-cell lymphoma. Common extranodal sites include skin, bone, soft tissue, and lung. Extranodal involvement indicates systemic disease and may require modified treatment approaches. Distinguishing primary cutaneous ALCL from systemic ALCL with skin involvement is clinically critical.
Documentation Requirements
- ✓Pathology confirming ALCL in extranodal tissue with CD30 positivity and ALK-negative status
- ✓Specific extranodal organ or site identified and documented
- ✓Biopsy of extranodal site confirming lymphoma
- ✓Distinction between primary extranodal and systemic disease with extranodal spread
- ✓Clinical staging
Commonly Confused Codes
C84.77 — ALCL ALK-negative, spleen: Spleen has its own code; not coded as extranodalC84.7A — ALCL ALK-negative, breast: Breast has its own specific code in the ALK-negative seriesC86.6 — Primary cutaneous CD30+ T-cell lymphoproliferative disorder: Distinct from systemic ALCL with skin involvementC84.69 — ALCL ALK-positive, extranodal: Different ALK status
Code Hierarchy
└C84Mature T/NK-cell lymphomas└C84.7Anaplastic large cell lymphoma, ALK-negative└C84.79Anaplastic large cell lymphoma, ALK-negative, extranodal and solid organ sites
└C84.79Anaplastic large cell lymphoma, ALK-negative, extranodal and solid organ sites