C84.47
BillablePeripheral T-cell lymphoma, not elsewhere classified, spleen
HCC Category Mapping
V28HCC 19 — Lymphoma and Other Cancers
0.105V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers
0.000What This Code Means
A type of cancer affecting T-cells (immune cells) that is not classified elsewhere, specifically involving the spleen.
Coding Tips
- •Verify documentation specifies the spleen as the primary site of involvement
- •Confirm this is peripheral T-cell lymphoma NOS and not a more specific subtype
Clinical Significance
Peripheral T-cell lymphoma not elsewhere classified with splenic involvement indicates systemic disease affecting this major lymphoid organ. Splenic involvement often presents with splenomegaly, cytopenias, and constitutional symptoms. Differentiating PTCL-NOS from hepatosplenic T-cell lymphoma (a distinct aggressive subtype) is critical for treatment and prognosis.
Documentation Requirements
- ✓Pathology confirming PTCL-NOS with immunophenotyping excluding hepatosplenic T-cell lymphoma
- ✓Imaging documenting splenic involvement (CT, PET/CT, or ultrasound showing splenomegaly or focal lesions)
- ✓Splenectomy pathology if applicable
- ✓Documentation distinguishing between primary splenic involvement and generalized disease
- ✓Active disease status documented
Commonly Confused Codes
C86.1 — Hepatosplenic T-cell lymphoma: A distinct entity with gamma-delta T-cell phenotype, sinusoidal infiltration pattern, and much worse prognosis; must be excluded before coding PTCL-NOS of spleenC84.43 — PTCL-NOS, intra-abdominal lymph nodes: Splenic involvement is separate from abdominal lymph node disease; the spleen is an organ, not a lymph nodeC84.48 — PTCL-NOS, multiple sites: If both spleen and lymph nodes are involved, coding guidance may direct to multiple sitesC84.49 — PTCL-NOS, extranodal/solid organ: The spleen has its own designated code (7th character 7), so use C84.47, not C84.49
Code Hierarchy
└C84Mature T/NK-cell lymphomas└C84.4Peripheral T-cell lymphoma, not elsewhere classified└C84.47Peripheral T-cell lymphoma, not elsewhere classified, spleen
└C84.47Peripheral T-cell lymphoma, not elsewhere classified, spleen