C84.75
BillableAnaplastic large cell lymphoma, ALK-negative, lymph nodes of inguinal region and lower limb
HCC Category Mapping
V28HCC 19 — Lymphoma and Other Cancers
0.105V24HCC 10 — Lymphoma and Other Cancers
0.675ESRDHCC 10 — Lymphoma and Other Cancers
0.000RxHCCHCC 21 — Hodgkin Lymphoma and Other Cancers
0.000What This Code Means
A type of aggressive lymphoma (cancer of immune cells) without a specific genetic marker (ALK-negative) that is located in the lymph nodes of the groin area and lower leg.
Coding Tips
- •Confirm inguinal and femoral lymph node involvement through physical examination findings or imaging documentation
- •Document unilateral versus bilateral involvement if specified in the clinical record
Clinical Significance
Anaplastic large cell lymphoma, ALK-negative, involving inguinal and lower limb lymph nodes indicates aggressive T-cell lymphoma in the groin and lower extremity nodal basins. ALK-negative status confers worse prognosis than ALK-positive disease. Inguinal lymphadenopathy requires pathologic confirmation to distinguish from infections, metastatic disease, or reactive causes.
Documentation Requirements
- ✓Pathology confirming ALCL with CD30 positivity and ALK-negative status
- ✓Physical exam or imaging documenting inguinal and/or lower limb lymph node involvement
- ✓T-cell lineage confirmed
- ✓Clinical staging
- ✓ALK testing methodology and result documented
Commonly Confused Codes
C84.65 — ALCL ALK-positive, inguinal/lower limb: Different ALK statusC84.45 — PTCL-NOS, inguinal/lower limb: Different lymphoma subtypeC84.76 — ALCL ALK-negative, intrapelvic: Deep pelvic nodes are distinct from superficial inguinal nodesC84.95 — Mature T/NK-cell lymphoma, unspecified, inguinal/lower limb: Less specific; use ALCL code when confirmed
Code Hierarchy
└C84Mature T/NK-cell lymphomas└C84.7Anaplastic large cell lymphoma, ALK-negative└C84.75Anaplastic large cell lymphoma, ALK-negative, lymph nodes of inguinal region and lower limb
└C84.75Anaplastic large cell lymphoma, ALK-negative, lymph nodes of inguinal region and lower limb