V28 HCC 108
Sickle Cell Disorders, Except Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero; Beta Thalassemia Major
Under the CMS-HCC V28 risk adjustment model (PY2026 Medicare Advantage), HCC 108 has a source-labeled community non-dual aged reference coefficient of 0.146, and 39 ICD-10-CM diagnosis codes appear in its official mapping. In the V28 hierarchy it is superseded by HCC 107 when a more severe category in the same disease group is also present.
RAF factors
The community factor varies by Medicaid and originally-disabled status; the institutional factor applies to long-term-institutional members. These are the CMS-HCC V28 PY2026 relative factors.
These are source-labeled code-level HCC coefficient references, not a full member score. Use the RAF Calculator with complete member context for CMS-HCC V28 PY2026. No score is shown unless every required source and calculation check passes.
V28 hierarchy
Trumped by: HCC 107 (a more severe category in the same disease group supersedes this one).
ICD-10-CM codes that map to HCC 108 (39)
ICD-10-CM codes in the official mapping for this category under CMS-HCC V28 PY2026. Open any code for its full description and coding guidance.
- D56.1Beta thalassemia
- D56.2Delta-beta thalassemia
- D56.5Hemoglobin E-beta thalassemia
- D57.20Sickle-cell/Hb-C disease without crisis
- D57.211Sickle-cell/Hb-C disease with acute chest syndrome
- D57.212Sickle-cell/Hb-C disease with splenic sequestration
- D57.213Sickle-cell/Hb-C disease with cerebral vascular involvement
- D57.214Sickle-cell/Hb-C disease with dactylitis
- D57.218Sickle-cell/Hb-C disease with crisis with other specified complication
- D57.219Sickle-cell/Hb-C disease with crisis, unspecified
- D57.40Sickle-cell thalassemia without crisis
- D57.411Sickle-cell thalassemia, unspecified, with acute chest syndrome
- D57.412Sickle-cell thalassemia, unspecified, with splenic sequestration
- D57.413Sickle-cell thalassemia, unspecified, with cerebral vascular involvement
- D57.414Sickle-cell thalassemia, unspecified, with dactylitis
- D57.418Sickle-cell thalassemia, unspecified, with crisis with other specified complication
- D57.419Sickle-cell thalassemia, unspecified, with crisis
- D57.44Sickle-cell thalassemia beta plus without crisis
- D57.451Sickle-cell thalassemia beta plus with acute chest syndrome
- D57.452Sickle-cell thalassemia beta plus with splenic sequestration
- D57.453Sickle-cell thalassemia beta plus with cerebral vascular involvement
- D57.454Sickle-cell thalassemia beta plus with dactylitis
- D57.458Sickle-cell thalassemia beta plus with crisis with other specified complication
- D57.459Sickle-cell thalassemia beta plus with crisis, unspecified
- D57.80Other sickle-cell disorders without crisis
- D57.811Other sickle-cell disorders with acute chest syndrome
- D57.812Other sickle-cell disorders with splenic sequestration
- D57.813Other sickle-cell disorders with cerebral vascular involvement
- D57.814Other sickle-cell disorders with dactylitis
- D57.818Other sickle-cell disorders with crisis with other specified complication
- D57.819Other sickle-cell disorders with crisis, unspecified
- H36.811Nonproliferative sickle-cell retinopathy, right eye
- H36.812Nonproliferative sickle-cell retinopathy, left eye
- H36.813Nonproliferative sickle-cell retinopathy, bilateral
- H36.819Nonproliferative sickle-cell retinopathy, unspecified eye
- H36.821Proliferative sickle-cell retinopathy, right eye
- H36.822Proliferative sickle-cell retinopathy, left eye
- H36.823Proliferative sickle-cell retinopathy, bilateral
- H36.829Proliferative sickle-cell retinopathy, unspecified eye
Coder workflow notes
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Frequently asked questions
What is CMS-HCC V28 category 108?
HCC 108 is "Sickle Cell Disorders, Except Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero; Beta Thalassemia Major", a Hierarchical Condition Category in the CMS-HCC V28 risk adjustment model (100% phase-in for payment year 2026). 39 ICD-10-CM codes appear in its official mapping.
What reference coefficient is published for HCC 108?
The source-labeled community non-dual aged reference coefficient for CMS-HCC V28 category 108 is 0.146. The exact coefficient varies by enrollment segment (community Medicaid and originally-disabled status, and institutional); the full segment table is published in the CMS V28 model files.
How many ICD-10-CM codes map to HCC 108?
39 ICD-10-CM diagnosis codes appear in the official mapping for CMS-HCC V28 category 108 (Sickle Cell Disorders, Except Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero; Beta Thalassemia Major) for payment year 2026.
Which categories trump HCC 108 in the V28 hierarchy?
HCC 108 is superseded by HCC 107 (Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero). When a more severe category in the same disease group is documented, it is counted instead of HCC 108.
Related references
Sources
CMS ICD-10-CM order-file billability plus the published mapping and CMS-HCC V28 PY2026 model software. CMS-HCC V28 model published at CMS.gov Risk Adjustors; ICD-10-CM member codes from the CMS ICD-10-CM code set.
Verified current to CMS-HCC V28, payment year 2026 — last reviewed May 30, 2026.