D57.813

HCC Category Mapping

What This Code Means

A rare sickle-cell disorder with stroke or blood vessel problems affecting the brain.

Coding Tips

• •Cerebral vascular involvement is a serious complication; ensure imaging or clinical evidence supports this diagnosis
• •Document whether this is a stroke, transient ischemic attack, or other cerebral vascular event

Clinical Significance

Other sickle-cell disorders with cerebral vascular involvement captures stroke or cerebrovascular events occurring in patients with rare sickle-cell variants. Sickle-cell disease is a major risk factor for both ischemic and hemorrhagic stroke, with cerebrovascular disease affecting up to 11% of sickle-cell patients by age 20. This condition may present as acute stroke, transient ischemic attack, or silent cerebral infarction, and requires urgent neurological evaluation and chronic transfusion therapy.

Documentation Requirements

• ✓Document the specific sickle-cell variant and the type of cerebrovascular event (ischemic stroke, hemorrhagic stroke, transient ischemic attack, or moyamoya disease).
• ✓Include neuroimaging results (magnetic resonance imaging, magnetic resonance angiography, or computed tomography).
• ✓Record neurological examination findings, National Institutes of Health Stroke Scale score if applicable, and any residual deficits.
• ✓Document treatment including exchange transfusion, chronic transfusion program, and hydroxyurea therapy.

Commonly Confused Codes