FY2027 ICD-10-CM reference
D57: Sickle-cell disorders
By the HCC Buddy Coding Team
The official ICD-10-CM descriptor is Sickle-cell disorders. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Nonbillable heading. Verified against the official FY2027 order file.
More specific FY2027 codes
- D57.0: Hb-SS disease with crisisNonbillable heading
- D57.1: Sickle-cell disease without crisisBillable code
- D57.2: Sickle-cell/Hb-C diseaseNonbillable heading
- D57.3: Sickle-cell traitBillable code
- D57.4: Sickle-cell thalassemiaNonbillable heading
- D57.8: Other sickle-cell disordersNonbillable heading
FY2027 Tabular instructions
Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.
Excludes2
autoimmune disease (systemic) NOS (M35.9)
Source: D50-D89 (chapter, inherited).
Excludes2
certain conditions originating in the perinatal period (P00-P96)
Source: D50-D89 (chapter, inherited).
Excludes2
complications of pregnancy, childbirth and the puerperium (O00-O9A)
Source: D50-D89 (chapter, inherited).
Excludes2
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
Source: D50-D89 (chapter, inherited).
Excludes2
endocrine, nutritional and metabolic diseases (E00-E88)
Source: D50-D89 (chapter, inherited).
Excludes2
human immunodeficiency virus [HIV] disease (B20)
Source: D50-D89 (chapter, inherited).
Excludes2
injury, poisoning and certain other consequences of external causes (S00-T88)
Source: D50-D89 (chapter, inherited).
Excludes2
neoplasms (C00-D49)
Source: D50-D89 (chapter, inherited).
Excludes2
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Source: D50-D89 (chapter, inherited).
Instructional note
code for any associated fever (R50.81)
Source: D57 (category, direct).
Excludes1
other hemoglobinopathies (D58.-)
Source: D57 (category, direct).
Compare the FY2027 additions, removals and billable-status changes
What does D57 mean in FY2027?
The official ICD-10-CM descriptor is Sickle-cell disorders. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Is D57 billable in FY2027?
The FY2027 order file marks D57 as a nonbillable heading. Select a complete billable child code.
Does D57 map to an HCC?
Risk-model mapping is not applicable to this nonbillable heading. Check a complete billable child code.
Source: CMS FY2027 ICD-10-CM order file. Payment model: CMS CY 2027 Rate Announcement. Read the FY2027 Official Guidelines.
Review the FY2026 April edition