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D57.459

Billable

Sickle-cell thalassemia beta plus with crisis, unspecified

HCC Category Mapping

V28HCC 108Sickle Cell Disorders and Thalassemia
0.607
V24HCC 46Severe Hematological Disorders
0.666
ESRDHCC 46Severe Hematological Disorders
0.000

What This Code Means

A sickle-cell thalassemia condition experiencing a crisis episode, but the specific type of crisis is not documented or specified.

Coding Tips

  • This is a default code when a crisis is present but the specific complication cannot be determined
  • Query the provider if possible to identify the specific crisis type for more accurate coding

Clinical Significance

Sickle-cell thalassemia beta plus with crisis represents a combined hemoglobinopathy where patients carry both sickle hemoglobin and beta-plus thalassemia trait, currently in an acute crisis state. The unspecified crisis designation means the documentation does not clarify whether the crisis involves vaso-occlusive pain, acute chest syndrome, splenic sequestration, or cerebral vascular events. These patients require urgent evaluation and management, and the lack of crisis specificity represents a documentation gap that should be addressed through provider query.

Documentation Requirements

  • Document the specific type of crisis (vaso-occlusive, acute chest syndrome, splenic sequestration, cerebral vascular involvement, or dactylitis).
  • Record hemoglobin electrophoresis results confirming beta-plus thalassemia variant.
  • Include current hemoglobin/hematocrit levels, reticulocyte count, and any end-organ damage.
  • Document pain severity, location, and duration if vaso-occlusive crisis is present.

Commonly Confused Codes

Code Hierarchy

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