Skip to content

N16 ICD-10-CM Code: Renal tubulo-interstitial disorders in diseases classified elsewhere

ICD-10-CM Code View

HCC Buddy Code Card

Digital ICD-10 code-book layout with official code detail, always-visible risk models, Code Trumping, and Buddy coding guidance.

FY 2026 Apr update / Diseases of the genitourinary system (N00-N99) / Renal tubulo-interstitial diseases (N10-N16)

N16

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Renal tubulo-interstitial disorders in diseases classified elsewhere

Kidney disease affecting the tubules and interstitium that occurs as a complication of another disease classified elsewhere in the ICD-10 system. The kidney damage is secondary to another primary condition.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
N1Renal tubulo-interstitial diseases (N10-N16)
N16Renal tubulo-interstitial disorders in diseases classified elsewhere

Inclusion Terms

Official
  • Pyelonephritis
  • Tubulo-interstitial nephritis

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for N16 in this effective period.

Related Child Codes

Official

ICD-10-CM does not list child codes under N16 for this display context.

Includes

Official

ICD-10-CM does not list Includes notes for N16 in this effective period.

Excludes 1

Official
  • diphtheritic pyelonephritis and tubulo-interstitial nephritis (A36.84)
  • pyelonephritis and tubulo-interstitial nephritis in candidiasis (B37.49)
  • pyelonephritis and tubulo-interstitial nephritis in cystinosis (E72.04)
  • pyelonephritis and tubulo-interstitial nephritis in salmonella infection (A02.25)
  • pyelonephritis and tubulo-interstitial nephritis in sarcoidosis (D86.84)

Code First

Official
  • underlying disease, such as:
  • brucellosis (A23.0-A23.9)
  • cryoglobulinemia (D89.1)
  • glycogen storage disease (E74.0-)
  • leukemia (C91-C95)

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for N16 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for N16 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
This code requires a secondary code to identify the underlying disease causing the kidney damage; always code both conditions
Common underlying conditions include diabetes, systemic lupus erythematosus, and infections; ensure the primary condition is documented and coded

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is N16 an HCC code?

No. N16 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

Coder workflow notes

Get the V28 RAF + MEAT cheat sheet

One printable page: confirm a code's V28 HCC status, its RAF weight, and the MEAT your note needs to make it stick. Free, no card.

Free PDF. No card. Unsubscribe anytime.

This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

N16 is the ICD-10-CM diagnosis code for renal tubulo-interstitial disorders in diseases classified elsewhere. Kidney disease affecting the tubules and interstitium that occurs as a complication of another disease classified elsewhere in the ICD-10 system. The kidney damage is secondary to another primary condition. N16 sits in the ICD-10-CM chapter for diseases of the genitourinary system (n00-n99), within the section covering renal tubulo-interstitial diseases (n10-n16).

N16 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

This code requires a secondary code to identify the underlying disease causing the kidney damage; always code both conditions.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for N16 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • This code requires a secondary code to identify the underlying disease causing the kidney damage; always code both conditions
  • Common underlying conditions include diabetes, systemic lupus erythematosus, and infections; ensure the primary condition is documented and coded

Excludes 1, Do NOT code together

  • diphtheritic pyelonephritis and tubulo-interstitial nephritis (A36.84)
  • pyelonephritis and tubulo-interstitial nephritis in candidiasis (B37.49)
  • pyelonephritis and tubulo-interstitial nephritis in cystinosis (E72.04)
  • pyelonephritis and tubulo-interstitial nephritis in salmonella infection (A02.25)
  • pyelonephritis and tubulo-interstitial nephritis in sarcoidosis (D86.84)
  • pyelonephritis and tubulo-interstitial nephritis in Sjogren syndrome (M35.04)
  • pyelonephritis and tubulo-interstitial nephritis in systemic lupus erythematosus (M32.15)
  • pyelonephritis and tubulo-interstitial nephritis in toxoplasmosis (B58.83)
  • renal tubular degeneration in diabetes (E08-E13 with .29)
  • syphilitic pyelonephritis and tubulo-interstitial nephritis (A52.75)

Code First

Code Hierarchy

N16Renal tubulo-interstitial disorders in diseases classified elsewhere
N16Renal tubulo-interstitial disorders in diseases classified elsewhere

Work N16 in HCC Buddy

Open N16 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 14 days to try everything.