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C81.0 ICD-10-CM Code: Nodular lymphocyte predominant Hodgkin lymphoma

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FY 2026 Apr update / Neoplasms (C00-D49) / Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)

C81.0

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Nodular lymphocyte predominant Hodgkin lymphoma

Nodular lymphocyte predominant Hodgkin lymphoma

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
C81Hodgkin lymphoma
C81.0Nodular lymphocyte predominant Hodgkin lymphoma

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for C81.0 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for C81.0 in this effective period.

Related Child Codes

Official
C81.00Nodular lymphocyte predominant Hodgkin lymphoma, unspecified site
C81.01Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of head, face, and neck
C81.02Nodular lymphocyte predominant Hodgkin lymphoma, intrathoracic lymph nodes
C81.03Nodular lymphocyte predominant Hodgkin lymphoma, intra-abdominal lymph nodes
C81.04Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of axilla and upper limb

Includes

Official

ICD-10-CM does not list Includes notes for C81.0 in this effective period.

Excludes 1

Official
  • personal history of Hodgkin lymphoma (Z85.71)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for C81.0 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for C81.0 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for C81.0 in this effective period.

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

What This Code Means

C81.0 is the ICD-10-CM diagnosis code for nodular lymphocyte predominant hodgkin lymphoma. C81.0 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of lymphoid, hematopoietic and related tissue (c81-c96).

Header codes like C81.0 cannot be reported on claims directly, they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at C81.0's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for C81.0 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Child Codes

Code Hierarchy

C81Hodgkin lymphomaC81.0Nodular lymphocyte predominant Hodgkin lymphoma
C81.0Nodular lymphocyte predominant Hodgkin lymphoma

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