Opportunistic Infections
Under the CMS-HCC V28 risk adjustment model (PY2026 Medicare Advantage), HCC 6 carries a community non-dual aged RAF of 0.381, and 37 payable ICD-10-CM diagnosis codes map to it.
RAF factors
The community factor varies by Medicaid and originally-disabled status; the institutional factor applies to long-term-institutional members. These are the CMS-HCC V28 PY2026 relative factors.
ICD-10-CM codes that map to HCC 6 (37)
Payable diagnosis codes that map to this category under CMS-HCC V28 PY2026. Open any code for its full description, HCC mapping, and coding guidance.
- A07.2Cryptosporidiosis
- A31.0Pulmonary mycobacterial infection
- A31.2Disseminated mycobacterium avium-intracellulare complex (DMAC)
- B25.0Cytomegaloviral pneumonitis
- B25.1Cytomegaloviral hepatitis
- B25.2Cytomegaloviral pancreatitis
- B25.8Other cytomegaloviral diseases
- B25.9Cytomegaloviral disease, unspecified
- B37.1Pulmonary candidiasis
- B37.7Candidal sepsis
- B37.81Candidal esophagitis
- B44.0Invasive pulmonary aspergillosis
- B44.1Other pulmonary aspergillosis
- B44.2Tonsillar aspergillosis
- B44.7Disseminated aspergillosis
- B44.89Other forms of aspergillosis
- B44.9Aspergillosis, unspecified
- B45.0Pulmonary cryptococcosis
- B45.1Cerebral cryptococcosis
- B45.2Cutaneous cryptococcosis
- B45.3Osseous cryptococcosis
- B45.7Disseminated cryptococcosis
- B45.8Other forms of cryptococcosis
- B45.9Cryptococcosis, unspecified
- B46.0Pulmonary mucormycosis
- B46.1Rhinocerebral mucormycosis
- B46.2Gastrointestinal mucormycosis
- B46.3Cutaneous mucormycosis
- B46.4Disseminated mucormycosis
- B46.5Mucormycosis, unspecified
- B46.8Other zygomycoses
- B46.9Zygomycosis, unspecified
- B48.4Penicillosis
- B48.8Other specified mycoses
- B58.2Toxoplasma meningoencephalitis
- B58.3Pulmonary toxoplasmosis
- B59Pneumocystosis
Frequently asked questions
What is CMS-HCC V28 category 6?
HCC 6 is "Opportunistic Infections", a payment Hierarchical Condition Category in the CMS-HCC V28 risk adjustment model (100% phase-in for payment year 2026). 37 payable ICD-10-CM codes map to it.
What is the RAF weight for HCC 6?
The community non-dual aged relative factor for CMS-HCC V28 category 6 is 0.381. The exact factor varies by enrollment segment (community Medicaid and originally-disabled status, and institutional); the full segment table is published in the CMS V28 Rate Announcement.
How many ICD-10-CM codes map to HCC 6?
37 payable ICD-10-CM diagnosis codes map to CMS-HCC V28 category 6 (Opportunistic Infections) for payment year 2026.
Source: CMS published ICD-10-CM mapping file plus CMS-HCC v28 PY2026 model software.