FY2027 ICD-10-CM reference
B25.8: Other cytomegaloviral diseases
By the HCC Buddy Coding Team
The official ICD-10-CM descriptor is Other cytomegaloviral diseases. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Billable code. Verified against the official FY2027 order file.
FY2027 Tabular instructions
Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.
Includes
diseases generally recognized as communicable or transmissible
Source: A00-B99 (chapter, inherited).
Instructional note
code to identify resistance to antimicrobial drugs (Z16.-)
Source: A00-B99 (chapter, inherited).
Excludes2
carrier or suspected carrier of infectious disease (Z22.-)
Source: A00-B99 (chapter, inherited).
Excludes2
certain localized infections - see body system-related chapters
Source: A00-B99 (chapter, inherited).
Excludes2
infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
Source: A00-B99 (chapter, inherited).
Excludes2
infectious and parasitic diseases specific to the perinatal period (P35-P39)
Source: A00-B99 (chapter, inherited).
Excludes2
influenza and other acute respiratory infections (J00-J22)
Source: A00-B99 (chapter, inherited).
Excludes1
congenital cytomegalovirus infection (P35.1)
Source: B25 (category, inherited).
Excludes1
cytomegaloviral mononucleosis (B27.1-)
Source: B25 (category, inherited).
Instructional note
Cytomegaloviral encephalitis
Source: B25.8 (self, direct).
Compare the FY2027 additions, removals and billable-status changes
What does B25.8 mean in FY2027?
The official ICD-10-CM descriptor is Other cytomegaloviral diseases. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Is B25.8 billable in FY2027?
The FY2027 order file marks B25.8 as billable. Check the complete Tabular instructions and documentation before assigning it.
Does B25.8 map to an HCC?
In the CMS 2027 Initial ICD-10-CM Mappings (payment year 2027, 2026 dates of service), B25.8 maps to CMS-HCC V28 HCC 6 (Opportunistic Infections). For 2027 dates of service, CMS has not yet published the payment year 2028 mappings. Under the PY2026 CMS mapping; CMS 2027 initial file unchanged: ESRD HCC 6; RxHCC HCC 5. Coefficients for these models are pending verification for payment year 2027. HHS-HCC: HCC 6 under the HHS-HCC 2026 benefit year mapping (no RAF; HHS-HCC weights vary by metal level). CMS-HCC V24: not used for payment year 2027 Medicare Advantage payment (CMS CY 2027 Rate Announcement). The PACE mapping is still pending verification for FY2027.
Source: CMS FY2027 ICD-10-CM order file. Payment model: CMS CY 2027 Rate Announcement. Read the FY2027 Official Guidelines.
Review the FY2026 April edition