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B46.8

Billable

Other zygomycoses

Last updated: FY2026 ICD-10-CM (Oct 1, 2025 – Sep 30, 2026) | CMS-HCC V28 (100% phase-in, PY2026)

Is B46.8 an HCC code?

Yes. B46.8 maps to Opportunistic Infections under the CMS-HCC V28 risk adjustment model (and Opportunistic Infections under V24).

HCC Category Mapping

V28HCC 6Opportunistic Infections
0.381
V24HCC 6Opportunistic Infections
0.424
ESRDHCC 6Opportunistic Infections
0.076
RxHCCHCC 5Opportunistic Infections
0.468

RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

MEAT Criteria for B46.8

For B46.8to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically — it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed B46.8 during that encounter — not just copy-forwarded from a problem list.

What This Code Means

B46.8 is the ICD-10-CM diagnosis code for other zygomycoses. Other types of fungal infections caused by zygomycete fungi (a broader fungal family) that are not mucormycosis. B46.8 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering mycoses (b35-b49).

Under the CMS-HCC V28 risk adjustment model, B46.8 maps to Opportunistic Infections (HCC 6) with a community, non-dual, aged base RAF weight of 0.381. Under the older V24 model, B46.8 mapped to the same category but with a base RAF weight of 0.424 — V28 recalibrated weights across the entire model. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

Document the specific type of zygomycosis if identified. Because B46.8 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for B46.8 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Document the specific type of zygomycosis if identified
  • Ensure this is not mucormycosis, which has its own specific codes

Clinical Significance

Other zygomycoses captures infections caused by zygomycete fungi other than Mucorales, including entomophthoramycosis (Basidiobolus and Conidiobolus species). These infections differ from mucormycosis in that they can affect immunocompetent patients and tend to be more chronic and indolent. They are predominantly found in tropical regions.

Documentation Requirements

  • Culture or histopathologic identification of the specific zygomycete organism
  • Documentation that this is NOT mucormycosis (different genus within Zygomycetes)
  • Clinical presentation: subcutaneous nodules, facial swelling (Conidiobolus), or limb/trunk masses (Basidiobolus)
  • Geographic/travel history to tropical or subtropical endemic areas
  • Immune status of the patient documented

Commonly Confused Codes

  • B46.0-B46.5 (Mucormycosis codes) - mucormycosis is the most common zygomycosis and has its own specific codes
  • B46.9 (Zygomycosis, unspecified) - use only when the specific organism cannot be determined
  • B48.8 (Other specified mycoses) - for fungal infections not classified as zygomycoses

Code Hierarchy

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B46.8 ICD-10 Code: Other zygomycoses | | HCC Buddy