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A31.2 ICD-10-CM Code: Disseminated mycobacterium avium-intracellulare complex (DMAC)

A31.2 maps to CMS-HCC V28 6 (RAF 0.381). Documentation must support MEAT. MEAT criteria · RAF calculator · HCC Buddy coding tools

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FY 2026 Apr update / Certain infectious and parasitic diseases (A00-B99) / Other bacterial diseases (A30-A49)

A31.2

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Disseminated mycobacterium avium-intracellulare complex (DMAC)

A serious infection caused by mycobacterium avium-intracellulare bacteria that has spread throughout the body, most commonly occurring in people with weakened immune systems such as those with advanced HIV/AIDS. This infection affects multiple organ systems and requires prolonged antibiotic treatment.

Buddy the Bee presenting code insight

Buddy Insight

Disseminated Mycobacterium avium-intracellulare complex (DMAC) is a severe systemic infection occurring almost exclusively in profoundly immunocompromised patients, particularly those with AIDS and CD4 counts below 50.

CMS-HCC V28

HCC 6

RAF 0.381

CMS-HCC V24

HCC 6

RAF 0.424

ACA/HHS

HCC 6

Varies by metal level

ESRD/PACE

HCC 6

RAF 0.076

RXHCC

HCC 5

RAF 0.468

Code Book Path

Official
A31Infection due to other mycobacteria
A31.2Disseminated mycobacterium avium-intracellulare complex (DMAC)

Inclusion Terms

Official
  • MAC sepsis

Excludes 2

Official
  • leprosy (A30.-)
  • tuberculosis (A15-A19)

Related Child Codes

Official
A31.0Pulmonary mycobacterial infection
A31.1Cutaneous mycobacterial infection
A31.8Other mycobacterial infections
A31.9Mycobacterial infection, unspecified

Includes

Official

ICD-10-CM does not list Includes notes for A31.2 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for A31.2 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for A31.2 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for A31.2 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for A31.2 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Blood culture or tissue biopsy positive for Mycobacterium avium complex (MAC)
Evidence of disseminated disease (involvement of 2+ organ systems: blood, bone marrow, liver, lymph nodes)
CD4 count documentation (typically below 50 cells/mm3 in HIV patients)
HIV/AIDS status with B20 coding when applicable

MEAT Support

HCC Buddy guidance
Blood culture or tissue biopsy positive for Mycobacterium avium complex (MAC)
Evidence of disseminated disease (involvement of 2+ organ systems: blood, bone marrow, liver, lymph nodes)
CD4 count documentation (typically below 50 cells/mm3 in HIV patients)
HIV/AIDS status with B20 coding when applicable

Audit Caution

HCC Buddy guidance
In HIV/AIDS patients, sequence B20 first with A31.2 as an additional code for the opportunistic infection
Disseminated means involvement beyond a single organ — do not code A31.2 for pulmonary-only MAC disease
MAC prophylaxis in HIV patients (CD4 <50) does not warrant coding A31.2 — only code when active disease is diagnosed
Do not confuse with M. tuberculosis disseminated disease, which is coded under A19 series

Common Mistakes

HCC Buddy guidance
A31.0 (Pulmonary mycobacterial infection) — Use A31.0 for lung-only NTM disease; A31.2 is for disseminated (multi-organ) MAC disease
A15 series (Tuberculosis) — MAC is nontuberculous; completely different organism requiring different treatment
B20 (HIV disease) — Code B20 as the underlying condition with A31.2 as the manifestation in HIV/AIDS patients

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is A31.2 an HCC code?

Yes. A31.2 (Disseminated mycobacterium avium-intracellulare complex (DMAC)) maps to Opportunistic Infections under the CMS-HCC V28 risk adjustment model (and Opportunistic Infections under V24), with a community non-dual aged RAF of 0.381. It is billable for payment year 2026.

Coder answer: A31.2 is billable and maps to V28 HCC 6, Opportunistic Infections. Open it in the Code Book for the tabular path, RAF, and MEAT checklist.

Code
A31.2
Description
Disseminated mycobacterium avium-intracellulare complex (DMAC)
HCC (V28)
HCC 6 — Opportunistic Infections
RAF
0.381
Billable
Yes
Payment year
2026

HCC Category Mapping

V28HCC 6, Opportunistic Infections
0.381
V24HCC 6, Opportunistic Infections
0.424
ESRDHCC 6, Opportunistic Infections
0.076
RxHCCHCC 5, Opportunistic Infections
0.468

Each model's RAF is its CMS base weight for that model's standard population, so weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

Work A31.2 in the Code Book — tabular path, V28 RAF, and MEAT checklist →

MEAT Criteria for A31.2

For A31.2 to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed A31.2 during that encounter, not just copy-forwarded from a problem list.

Coder workflow notes

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What This Code Means

A31.2 is the ICD-10-CM diagnosis code for disseminated mycobacterium avium-intracellulare complex (dmac). A serious infection caused by mycobacterium avium-intracellulare bacteria that has spread throughout the body, most commonly occurring in people with weakened immune systems such as those with advanced HIV/AIDS. This infection affects multiple organ systems and requires prolonged antibiotic treatment. A31.2 sits in the ICD-10-CM chapter for certain infectious and parasitic diseases (a00-b99), within the section covering other bacterial diseases (a30-a49).

Under the CMS-HCC V28 risk adjustment model, A31.2 maps to Opportunistic Infections (HCC 6) with a community, non-dual, aged base RAF weight of 0.381. Under the older V24 model, A31.2 mapped to the same category but with a base RAF weight of 0.424, V28 recalibrated weights across the entire model. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

DMAC is typically an opportunistic infection in immunocompromised patients; always code the underlying immunodeficiency condition (such as B20 for HIV) as an additional diagnosis. Because A31.2 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for A31.2 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • DMAC is typically an opportunistic infection in immunocompromised patients; always code the underlying immunodeficiency condition (such as B20 for HIV) as an additional diagnosis
  • Verify documentation specifies 'disseminated' status; localized MAC infections are coded differently (A31.0 or A31.1), so confirm the infection has spread beyond a single site

Clinical Significance

Disseminated Mycobacterium avium-intracellulare complex (DMAC) is a severe systemic infection occurring almost exclusively in profoundly immunocompromised patients, particularly those with AIDS and CD4 counts below 50. It is an AIDS-defining illness that significantly worsens prognosis and requires lifelong suppressive therapy unless immune reconstitution occurs.

Documentation Requirements

  • Blood culture or tissue biopsy positive for Mycobacterium avium complex (MAC)
  • Evidence of disseminated disease (involvement of 2+ organ systems: blood, bone marrow, liver, lymph nodes)
  • CD4 count documentation (typically below 50 cells/mm3 in HIV patients)
  • HIV/AIDS status with B20 coding when applicable
  • Treatment regimen documented (typically clarithromycin/azithromycin + ethambutol + rifabutin)

Commonly Confused Codes

  • A31.0 (Pulmonary mycobacterial infection): Use A31.0 for lung-only NTM disease; A31.2 is for disseminated (multi-organ) MAC disease
  • A15 series (Tuberculosis): MAC is nontuberculous; completely different organism requiring different treatment
  • B20 (HIV disease): Code B20 as the underlying condition with A31.2 as the manifestation in HIV/AIDS patients

Child Codes

Code Hierarchy

Because A31.2 maps to a payment HCC, the documentation must also satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's risk adjustment score.

A31.2 maps to CMS-HCC V28 category 6, Opportunistic Infections. See the ICD-10 to HCC mapping hub for how the V28 crosswalk works. Because A31.2 carries a payment HCC, you can see what it adds to a RAF score and check the documentation the chart needs before it is submitted.

Work A31.2 in HCC Buddy

Open A31.2 in the Code Book for the full Index-to-Tabular path, MEAT checklist, and V28 HCC mapping, or in the Encoder to code from a keyword search. Pro includes 7 days to try everything, no card required.