B25.9
BillableCytomegaloviral disease, unspecified
HCC Category Mapping
V28HCC 6 — Opportunistic Infections
0.439V24HCC 6 — Opportunistic Infections
0.440ESRDHCC 6 — Opportunistic Infections
0.000RxHCCHCC 5 — Opportunistic Infections
0.000What This Code Means
A viral infection caused by cytomegalovirus (CMV) where the specific affected body part or system is not documented or identified.
Coding Tips
- •Use this code only when the documentation does not specify which organ system is affected by CMV; if a specific site is documented, use a more specific B25 code
- •Common in immunocompromised patients; review clinical context to determine if a more specific code applies
Clinical Significance
Cytomegaloviral disease, unspecified, is used when CMV infection is documented but the specific organ system affected is not identified. This code should prompt a query to the provider for site specification, as the clinical management and documentation quality improve with site-specific coding.
Documentation Requirements
- ✓Confirmed CMV infection (positive CMV PCR, culture, or antigen test)
- ✓Documentation that a specific organ involvement could not be determined
- ✓Clinical context: symptoms, immunocompromised status
- ✓Plans for further diagnostic workup to identify the affected organ system
- ✓Treatment regimen documented (empiric antiviral therapy)
Commonly Confused Codes
B25.0-B25.8 — Site-specific CMV codes; always prefer these over the unspecified code when organ involvement is documentedB27.10 (Cytomegaloviral mononucleosis without complications) — CMV mononucleosis in immunocompetent patients has a separate codeZ22.6 (Carrier of human T-lymphotropic virus type-1) — Different viral carrier state, not CMV
Code Hierarchy
└B25Cytomegaloviral disease└B25.9Cytomegaloviral disease, unspecified
└B25.9Cytomegaloviral disease, unspecified