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E23 ICD-10-CM Code: Hypofunction and other disorders of the pituitary gland

ICD-10-CM Code View

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FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Disorders of other endocrine glands (E20-E35)

E23

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Hypofunction and other disorders of the pituitary gland

Hypofunction and other disorders of the pituitary gland

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
E2Disorders of other endocrine glands (E20-E35)
E23Hypofunction and other disorders of the pituitary gland

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for E23 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for E23 in this effective period.

Related Child Codes

Official
E23.0Hypopituitarism
E23.1Drug-induced hypopituitarism
E23.2Diabetes insipidus
E23.3Hypothalamic dysfunction, not elsewhere classified
E23.6Other disorders of pituitary gland

Includes

Official
  • the listed conditions whether the disorder is in the pituitary or the hypothalamus

Excludes 1

Official
  • postprocedural hypopituitarism (E89.3)
  • short stature due to endocrine disorder (E34.3-)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for E23 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for E23 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for E23 in this effective period.

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Coder workflow notes

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What This Code Means

E23 is the ICD-10-CM diagnosis code for hypofunction and other disorders of the pituitary gland. E23 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering disorders of other endocrine glands (e20-e35).

Header codes like E23 cannot be reported on claims directly, they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at E23's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for E23 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Includes

  • the listed conditions whether the disorder is in the pituitary or the hypothalamus

Excludes 1, Do NOT code together

  • postprocedural hypopituitarism (E89.3)
  • short stature due to endocrine disorder (E34.3-)

Child Codes

Code Hierarchy

E23Hypofunction and other disorders of the pituitary gland
E23Hypofunction and other disorders of the pituitary gland

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