E23.0

Billable

Hypopituitarism

HCC Category Mapping

V24HCC 23 — Other Significant Endocrine and Metabolic Disorders

0.230

ESRDHCC 23 — Other Significant Endocrine and Metabolic Disorders

0.000

RxHCCHCC 43 — Other Significant Endocrine and Metabolic Disorders

0.000

What This Code Means

A condition where the pituitary gland produces insufficient hormones, resulting in deficiencies of growth hormone, thyroid hormone, cortisol, or other pituitary-regulated hormones.

Coding Tips

•Document which specific pituitary hormones are deficient, as this guides treatment and may require additional codes for secondary conditions
•Identify the underlying cause (tumor, surgery, radiation, trauma) if documented, as this may affect coding and treatment planning

Clinical Significance

Hypopituitarism represents deficient hormone production by the pituitary gland, which can involve single or multiple hormone axes. This condition requires lifelong hormone replacement and carries significant morbidity including adrenal crisis, hypothyroidism, growth failure, and reproductive dysfunction if untreated.

Documentation Requirements

✓Document which specific pituitary hormones are deficient (growth hormone, adrenocorticotropic hormone, thyroid-stimulating hormone, gonadotropins, antidiuretic hormone), underlying cause (tumor, surgery, radiation, Sheehan syndrome, trauma), hormone replacement therapy, and monitoring plan.

Use Additional Code

code, if applicable, for associated cachexia (E88.A)

Commonly Confused Codes

E23.1 (drug-induced hypopituitarism when caused by medication), E23.7 (unspecified pituitary disorder), E89.3 (postprocedural hypopituitarism following surgery or radiation), E23.6 (other pituitary disorders).