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E85 ICD-10-CM Code: Amyloidosis

E85 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · free HCC coding tools

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Code lookupE85

FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Metabolic disorders (E70-E88)

E85

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Amyloidosis

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Inclusion Terms

Official

No inclusion terms are included in this display for E85. Check the code and parent instructions in the Code Book.

Excludes 2

Official
  • Alzheimer's disease (G30.0-)
  • Ehlers-Danlos syndromes (Q79.6-)Inherited from E70-E88

Includes

Official

No Includes notes are included in this display for E85. Check the code and parent instructions in the Code Book.

Excludes 1

Official
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)Inherited from E00-E89, E70-E88
  • androgen insensitivity syndrome (E34.5-)Inherited from E00-E89, E70-E88
  • congenital adrenal hyperplasia (E25.0)Inherited from E00-E89, E70-E88
  • hemolytic anemias attributable to enzyme disorders (D55.-)Inherited from E00-E89, E70-E88
  • Marfan syndrome (Q87.4-)Inherited from E00-E89, E70-E88
  • 5-alpha-reductase deficiency (E29.1)Inherited from E00-E89, E70-E88

Code First

Official

No Code First sequencing instructions are included in this display for E85. Check the code and parent instructions in the Code Book.

Use Additional

Official

No Use Additional Code instructions are included in this display for E85. Check the code and parent instructions in the Code Book.

Code Also

Official

No Code Also instructions are included in this display for E85. Check the code and parent instructions in the Code Book.

Buddy Documentation Tip

HCC Buddy guidance
E85 is a non-billable category for amyloidosis. Move through the official child-code path until the documented detail supports a reportable code.
For this DOS, capture the provider's current assessment and the care action documented for amyloidosis. Keep the checklist tied to the note.
Do not swap E85 with E85.0. The FY2026 tabular describes E85.0 as non-neuropathic heredofamilial amyloidosis. Follow the documented detail.
Ask Buddy to show the official notes for E85 or compare its code path with E85.0.

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Code
E85
Description
Amyloidosis
HCC (V28)
No CMS-HCC V28 mapping
RAF reference coefficient
Billable
No
Payment year
2026

Coder workflow notes

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What This Code Means

E85 is the ICD-10-CM diagnosis code for amyloidosis. E85 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering metabolic disorders (e70-e88).

E85 is a non-billable category for amyloidosis. Move through the official child-code path until the documented detail supports a reportable code.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for E85 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • E85 is a non-billable category for amyloidosis. Move through the official child-code path until the documented detail supports a reportable code.
  • For this DOS, capture the provider's current assessment and the care action documented for amyloidosis. Keep the checklist tied to the note.
  • Do not swap E85 with E85.0. The FY2026 tabular describes E85.0 as non-neuropathic heredofamilial amyloidosis. Follow the documented detail.
  • Ask Buddy to show the official notes for E85 or compare its code path with E85.0.

Excludes 2, Not included here, may code separately

  • Alzheimer's disease (G30.0-)

Child Codes

Code Hierarchy

E85Amyloidosis
E85Amyloidosis

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