E85.9
BillableAmyloidosis, unspecified
HCC Category Mapping
V28HCC 50 — Glycogen/Amino-Acid/Other Metabolic Disorders
0.289V24HCC 23 — Other Significant Endocrine and Metabolic Disorders
0.230ESRDHCC 23 — Other Significant Endocrine and Metabolic Disorders
0.000What This Code Means
Amyloidosis where the specific type or cause has not been determined or is not specified in the medical record.
Coding Tips
- •This is a non-specific code; query the provider to determine the type of amyloidosis (AL, ATTR, or other) when possible
- •Use only when the type cannot be determined from available documentation
Clinical Significance
Amyloidosis, unspecified is used when amyloid deposition is confirmed but the specific type has not been determined. This code should prompt a query to the provider for specification, as different amyloidosis types have vastly different treatments and prognoses. It still captures HCC value but lacks the clinical specificity needed for optimal care.
Documentation Requirements
- ✓Confirmed amyloidosis diagnosis by the treating provider
- ✓Evidence of amyloid deposition (biopsy results if available)
- ✓Documentation that amyloid typing is pending or unavailable
- ✓Affected organ systems and clinical manifestations
- ✓Referral or plan for amyloid subtyping
- ✓Query to provider for type specification
Commonly Confused Codes
E85.81 — Light chain (AL) amyloidosis: most common systemic type, code when confirmedE85.82 — Wild-type transthyretin-related (ATTR) amyloidosis: increasingly diagnosed in elderly cardiac patientsE85.3 — Secondary systemic amyloidosis: code when secondary to chronic inflammatory diseaseE85.0 — Non-neuropathic heredofamilial amyloidosis: code when hereditary non-neuropathic form confirmed