FY2027 ICD-10-CM reference
E75: Disorders of sphingolipid metabolism and other lipid storage disorders
By the HCC Buddy Coding Team
The official ICD-10-CM descriptor is Disorders of sphingolipid metabolism and other lipid storage disorders. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Nonbillable heading. Verified against the official FY2027 order file.
CMS-HCC V28
Not applicable to this nonbillable heading
CMS-HCC V24
Not applicable to this nonbillable heading
ESRD
Not applicable to this nonbillable heading
PACE
Not applicable to this nonbillable heading
RxHCC
Not applicable to this nonbillable heading
HHS-HCC
Not applicable to this nonbillable heading
More specific FY2027 codes
- E75.0: GM2 gangliosidosisNonbillable heading
- E75.1: Other and unspecified gangliosidosisNonbillable heading
- E75.2: Other sphingolipidosisNonbillable heading
- E75.3: Sphingolipidosis, unspecifiedBillable code
- E75.4: Neuronal ceroid lipofuscinosisBillable code
- E75.5: Other lipid storage disordersBillable code
- E75.6: Lipid storage disorder, unspecifiedBillable code
FY2027 Tabular instructions
Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.
Instructional note
All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Source: E00-E89 (chapter, inherited).
Excludes1
transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Source: E00-E89 (chapter, inherited).
Excludes1
androgen insensitivity syndrome (E34.5-)
Source: E70-E88 (section, inherited).
Excludes1
congenital adrenal hyperplasia (E25.0)
Source: E70-E88 (section, inherited).
Excludes1
hemolytic anemias attributable to enzyme disorders (D55.-)
Source: E70-E88 (section, inherited).
Excludes1
Marfan syndrome (Q87.4-)
Source: E70-E88 (section, inherited).
Excludes1
5-alpha-reductase deficiency (E29.1)
Source: E70-E88 (section, inherited).
Excludes2
Ehlers-Danlos syndromes (Q79.6-)
Source: E70-E88 (section, inherited).
Excludes1
mucolipidosis, types I-III (E77.0-E77.1)
Source: E75 (category, direct).
Excludes1
Refsum's disease (G60.1)
Source: E75 (category, direct).
Compare the FY2027 additions, removals and billable-status changes
What does E75 mean in FY2027?
The official ICD-10-CM descriptor is Disorders of sphingolipid metabolism and other lipid storage disorders. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Is E75 billable in FY2027?
The FY2027 order file marks E75 as a nonbillable heading. Select a complete billable child code.
Does E75 map to an HCC?
Risk-model mapping is not applicable to this nonbillable heading. Check a complete billable child code.
Source: CMS FY2027 ICD-10-CM order file. Payment model: CMS CY 2027 Rate Announcement. Read the FY2027 Official Guidelines.
Review the FY2026 April edition