V28 HCC 114
Common Variable and Combined Immunodeficiencies
Under the CMS-HCC V28 risk adjustment model (PY2026 Medicare Advantage), HCC 114 has a source-labeled community non-dual aged reference coefficient of 2.262, and 18 ICD-10-CM diagnosis codes appear in its official mapping.
RAF factors
The community factor varies by Medicaid and originally-disabled status; the institutional factor applies to long-term-institutional members. These are the CMS-HCC V28 PY2026 relative factors.
These are source-labeled code-level HCC coefficient references, not a full member score. Use the RAF Calculator with complete member context for CMS-HCC V28 PY2026. No score is shown unless every required source and calculation check passes.
V28 hierarchy
Supersedes: HCC 115 (this category is counted instead of these when they co-occur).
ICD-10-CM codes that map to HCC 114 (18)
ICD-10-CM codes in the official mapping for this category under CMS-HCC V28 PY2026. Open any code for its full description and coding guidance.
- D81.0Severe combined immunodeficiency [SCID] with reticular dysgenesis
- D81.1Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
- D81.2Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
- D81.30Adenosine deaminase deficiency, unspecified
- D81.31Severe combined immunodeficiency due to adenosine deaminase deficiency
- D81.32Adenosine deaminase 2 deficiency
- D81.39Other adenosine deaminase deficiency
- D81.5Purine nucleoside phosphorylase [PNP] deficiency
- D81.6Major histocompatibility complex class I deficiency
- D81.7Major histocompatibility complex class II deficiency
- D81.82Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
- D81.89Other combined immunodeficiencies
- D81.9Combined immunodeficiency, unspecified
- D83.0Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
- D83.1Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
- D83.2Common variable immunodeficiency with autoantibodies to B- or T-cells
- D83.8Other common variable immunodeficiencies
- D83.9Common variable immunodeficiency, unspecified
Coder workflow notes
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Frequently asked questions
What is CMS-HCC V28 category 114?
HCC 114 is "Common Variable and Combined Immunodeficiencies", a Hierarchical Condition Category in the CMS-HCC V28 risk adjustment model (100% phase-in for payment year 2026). 18 ICD-10-CM codes appear in its official mapping.
What reference coefficient is published for HCC 114?
The source-labeled community non-dual aged reference coefficient for CMS-HCC V28 category 114 is 2.262. The exact coefficient varies by enrollment segment (community Medicaid and originally-disabled status, and institutional); the full segment table is published in the CMS V28 model files.
How many ICD-10-CM codes map to HCC 114?
18 ICD-10-CM diagnosis codes appear in the official mapping for CMS-HCC V28 category 114 (Common Variable and Combined Immunodeficiencies) for payment year 2026.
Related references
Sources
CMS ICD-10-CM order-file billability plus the published mapping and CMS-HCC V28 PY2026 model software. CMS-HCC V28 model published at CMS.gov Risk Adjustors; ICD-10-CM member codes from the CMS ICD-10-CM code set.
Verified current to CMS-HCC V28, payment year 2026 — last reviewed May 30, 2026.