D83.2

HCC Category Mapping

What This Code Means

A common immune disorder where the body produces antibodies that attack its own B or T immune cells, weakening the immune system.

Coding Tips

• •Document the presence of autoantibodies with specific testing results (e.g., anti-B cell or anti-T cell antibodies)
• •This code indicates an autoimmune component; document any associated autoimmune manifestations

Clinical Significance

Common variable immunodeficiency with autoantibodies to B- or T-cells represents a form of common variable immunodeficiency where the immune system produces antibodies that attack its own lymphocytes, contributing to the immunodeficiency through autoimmune destruction of B-cells or T-cells. This autoimmune component adds complexity to management and increases the risk of other autoimmune manifestations.

Documentation Requirements

• ✓Documentation must include serological evidence of autoantibodies directed against B-cells or T-cells, immunoglobulin levels confirming hypogammaglobulinemia, lymphocyte subset analysis, and documentation of any associated autoimmune cytopenias or other autoimmune conditions.
• ✓Describe the relationship between the autoantibodies and the clinical immunodeficiency, and include treatment approach addressing both immunodeficiency and autoimmune components.

Commonly Confused Codes