What is ICD-10 code D83.0?

D83.0 is the ICD-10-CM diagnosis code for Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function. A common immune disorder where the body doesn't produce enough antibodies or the B cells that make them don't function properly. D83.0 is a billable code, meaning it can be reported on a claim as a primary or secondary diagnosis when supported by documentation. D83.0 is part of the FY2026 ICD-10-CM code set published by the CMS National Center for Health Statistics and used on Medicare, Medicaid, and commercial claims in the United States.

Yes. D83.0 is a billable ICD-10-CM code that can be reported on professional and institutional claims as a primary or secondary diagnosis when the provider documentation supports the specific condition described. Billable codes in ICD-10-CM are coded to the highest level of specificity available for the documented diagnosis. D83.0 is current for fiscal year 2026 and remains in the active CMS ICD-10-CM code set published by the National Center for Health Statistics.

What is the V28 vs V24 difference for D83.0?

CMS phased in the V28 risk adjustment model over payment years 2024 (33%), 2025 (67%), and 2026 (100%), replacing V24. V28 consolidates HCC categories, removes some lower-acuity conditions, and recalibrates RAF weights across the entire model. For D83.0, V28 maps to Severe Combined Immunodeficiency and Other Immune Disorders at RAF 0.000 while V24 mapped to Disorders of Immunity at RAF 0.472. Both models can still appear in legacy data and in payer-specific lookback periods.

What should coders know when reporting D83.0?

Document specific B-cell count abnormalities and functional deficits from immunological testing Distinguish from D83.1 and D83.2 by confirming the primary problem is B-cell related, not T-cell or autoimmune Because D83.0 maps to a payment HCC, the documentation must also satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's risk adjustment score.

D83.0 ICD-10 Code: Common variable

ICD-10-CM Code View

HCC Buddy Code Card

Digital ICD-10 code-book layout with official code detail, always-visible risk models, Code Trumping, and Buddy coding guidance.

Code lookupD83.0Effective periodFY2026 Apr Update (Apr 1-Sep 30)

FY 2026 Apr update / Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) / Certain disorders involving the immune mechanism (D80-D89)

D83.0

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function

A common immune disorder where the body doesn't produce enough antibodies or the B cells that make them don't function properly.

Buddy Insight

CMS-HCC V28

Mapped

HCC 114

Severe Combined Immunodeficie...

RAF 0.0

CMS-HCC V24

Mapped

HCC 47

Disorders of Immunity

RAF 0.472

ACA/HHS

Not risk-adjusted for this model/period.

RAF 0

ESRD/PACE

Mapped

HCC 47

Disorders of Immunity

RAF 0.0

RXHCC

Mapped

HCC 99

Immunodeficiencies

RAF 0.0

Code Trumping

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Code Book Path

Official

D83Common variable immunodeficiency

D83.0Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for D83.0 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for D83.0 in this effective period.

Related Child Codes

Official

D83.1Common variable immunodeficiency with predominant immunoregulatory T-cell disorders

D83.2Common variable immunodeficiency with autoantibodies to B- or T-cells

D83.8Other common variable immunodeficiencies

D83.9Common variable immunodeficiency, unspecified

Includes

Official

ICD-10-CM does not list Includes notes for D83.0 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for D83.0 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for D83.0 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for D83.0 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for D83.0 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance

Documentation must include quantitative immunoglobulin levels (Immunoglobulin G, Immunoglobulin A, and often Immunoglobulin M significantly reduced), B-cell enumeration by flow cytometry, poor response to vaccination challenge testing, clinical manifestations including infection history, and treatment with immunoglobulin replacement therapy.

Specify that B-cell abnormalities are the predominant finding to justify D83.0 over D83.1 or D83.2.

MEAT Support

HCC Buddy guidance

Specify that B-cell abnormalities are the predominant finding to justify D83.0 over D83.1 or D83.2.

Audit Caution

HCC Buddy guidance

Common variable immunodeficiency requires at least two immunoglobulin classes significantly reduced and exclusion of other causes of hypogammaglobulinemia. Do not assign this code for medication-induced hypogammaglobulinemia (e.g., from rituximab) or protein-losing conditions. The B-cell abnormality must be documented as the predominant feature

if both T-cell and B-cell defects are equally prominent, D83.8 or D83.9 may be more appropriate.

Common Mistakes

HCC Buddy guidance

D83.1 (common variable immunodeficiency with predominant T-cell disorders), D83.2 (common variable immunodeficiency with autoantibodies to B

or T-cells), D83.9 (common variable immunodeficiency, unspecified, used when the predominant abnormality is not specified), D80.0 (hereditary hypogammaglobulinemia which typically presents earlier in life).

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is D83.0 an HCC code?

Yes. D83.0 maps to Severe Combined Immunodeficiency and Other Immune Disorders under the CMS-HCC V28 risk adjustment model (and Disorders of Immunity under V24).

HCC Category Mapping

V28HCC 114, Severe Combined Immunodeficiency and Other Immune Disorders

0.000

V24HCC 47, Disorders of Immunity

0.472

ESRDHCC 47, Disorders of Immunity

0.000

RxHCCHCC 99, Immunodeficiencies

0.000

RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

MEAT Criteria for D83.0

For D83.0to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
EEvaluate: test results, medication response, or physical findings reviewed by the provider
AAssess: explicit mention in the assessment or plan with acknowledgment of status
TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed D83.0 during that encounter, not just copy-forwarded from a problem list.

What This Code Means

D83.0 is the ICD-10-CM diagnosis code for common variable immunodeficiency with predominant abnormalities of b-cell numbers and function. A common immune disorder where the body doesn't produce enough antibodies or the B cells that make them don't function properly. D83.0 sits in the ICD-10-CM chapter for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (d50-d89), within the section covering certain disorders involving the immune mechanism (d80-d89).

Under the CMS-HCC V28 risk adjustment model, D83.0 maps to Severe Combined Immunodeficiency and Other Immune Disorders (HCC 114) with a community, non-dual, aged base RAF weight of 0.000. Under the older CMS-HCC V24 model, D83.0 maps to Disorders of Immunity (HCC 47) with a community, non-dual, aged base RAF weight of 0.472. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

Document specific B-cell count abnormalities and functional deficits from immunological testing. Because D83.0 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D83.0 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

•Document specific B-cell count abnormalities and functional deficits from immunological testing
•Distinguish from D83.1 and D83.2 by confirming the primary problem is B-cell related, not T-cell or autoimmune

Clinical Significance

Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function is the most common symptomatic primary immunodeficiency in adults, characterized by significantly reduced B-cell numbers or function leading to hypogammaglobulinemia. Patients present with recurrent sinopulmonary infections, gastrointestinal disease, granulomatous inflammation, and increased risk of autoimmune cytopenias and lymphoid malignancy.

Documentation Requirements

✓Documentation must include quantitative immunoglobulin levels (Immunoglobulin G, Immunoglobulin A, and often Immunoglobulin M significantly reduced), B-cell enumeration by flow cytometry, poor response to vaccination challenge testing, clinical manifestations including infection history, and treatment with immunoglobulin replacement therapy.
✓Specify that B-cell abnormalities are the predominant finding to justify D83.0 over D83.1 or D83.2.

Commonly Confused Codes

•D83.1 (common variable immunodeficiency with predominant T-cell disorders), D83.2 (common variable immunodeficiency with autoantibodies to B
•or T-cells), D83.9 (common variable immunodeficiency, unspecified, used when the predominant abnormality is not specified), D80.0 (hereditary hypogammaglobulinemia which typically presents earlier in life).