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S21 ICD-10-CM Code: Open wound of thorax

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FY 2026 Apr update / Injury, poisoning and certain other consequences of external causes (S00-T88) / Injuries to the thorax (S20-S29)

S21

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Open wound of thorax

Open wound of thorax

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
S2Injuries to the thorax (S20-S29)
S21Open wound of thorax

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for S21 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for S21 in this effective period.

Related Child Codes

Official
S21.0Open wound of breast
S21.1Open wound of front wall of thorax without penetration into thoracic cavity
S21.2Open wound of back wall of thorax without penetration into thoracic cavity
S21.3Open wound of front wall of thorax with penetration into thoracic cavity
S21.4Open wound of back wall of thorax with penetration into thoracic cavity

Includes

Official

ICD-10-CM does not list Includes notes for S21 in this effective period.

Excludes 1

Official
  • traumatic amputation (partial) of thorax (S28.1)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for S21 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for S21 in this effective period.

Code Also

Official
  • any associated injury, such as:
  • injury of heart (S26.-)
  • injury of intrathoracic organs (S27.-)
  • rib fracture (S22.3-, S22.4-)
  • spinal cord injury (S24.0-, S24.1-)

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

What This Code Means

S21 is the ICD-10-CM diagnosis code for open wound of thorax. S21 sits in the ICD-10-CM chapter for injury, poisoning and certain other consequences of external causes (s00-t88), within the section covering injuries to the thorax (s20-s29).

Header codes like S21 cannot be reported on claims directly, they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at S21's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for S21 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Excludes 1, Do NOT code together

  • traumatic amputation (partial) of thorax (S28.1)

Code Also

  • any associated injury, such as:
  • injury of heart (S26.-)
  • injury of intrathoracic organs (S27.-)
  • rib fracture (S22.3-, S22.4-)
  • spinal cord injury (S24.0-, S24.1-)
  • traumatic hemopneumothorax (S27.3)
  • traumatic hemothorax (S27.1)
  • traumatic pneumothorax (S27.0)
  • wound infection

Child Codes

Code Hierarchy

S21Open wound of thorax
S21Open wound of thorax

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