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O88.21 ICD-10-CM Code: Thromboembolism in pregnancy

ICD-10-CM Code View

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FY 2026 Apr update / Pregnancy, childbirth and the puerperium (O00-O9A) / Complications predominantly related to the puerperium (O85-O92)

O88.21

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Thromboembolism in pregnancy

Thromboembolism in pregnancy

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
O88Obstetric embolism
O88.2Obstetric thromboembolism
O88.21Thromboembolism in pregnancy

Inclusion Terms

Official
  • Obstetric (pulmonary) embolism NOS

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for O88.21 in this effective period.

Related Child Codes

Official
O88.211Thromboembolism in pregnancy, first trimester
O88.212Thromboembolism in pregnancy, second trimester
O88.213Thromboembolism in pregnancy, third trimester
O88.219Thromboembolism in pregnancy, unspecified trimester

Includes

Official

ICD-10-CM does not list Includes notes for O88.21 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for O88.21 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for O88.21 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for O88.21 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for O88.21 in this effective period.

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Code
O88.21
Description
Thromboembolism in pregnancy
HCC (V28)
No CMS-HCC V28 mapping
RAF
Billable
No
Payment year
2026

Coder workflow notes

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What This Code Means

O88.21 is the ICD-10-CM diagnosis code for thromboembolism in pregnancy. O88.21 sits in the ICD-10-CM chapter for pregnancy, childbirth and the puerperium (o00-o9a), within the section covering complications predominantly related to the puerperium (o85-o92).

Header codes like O88.21 cannot be reported on claims directly, they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at O88.21's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for O88.21 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Child Codes

Code Hierarchy

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