O43.021 ICD-10-CM Code: Fetus-to-fetus placental transfusion syndrome, first trimester
O43.021 is not a CMS-HCC payment code. MEAT criteria · RAF calculator · HCC Buddy coding tools
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FY 2026 Apr update / Pregnancy, childbirth and the puerperium (O00-O9A) / Maternal care related to the fetus and amniotic cavity and possible delivery problems (O30-O48)
O43.021
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceFetus-to-fetus placental transfusion syndrome, first trimester
An abnormal transfer of blood occurs between twins or multiples through a shared placenta during the first trimester of pregnancy.
CMS-HCC V28
N/A—
Not mapped
CMS-HCC V24
N/A—
Not mapped
ACA/HHS
MappedHCC 210
Varies by metal level
ESRD/PACE
N/A—
Not mapped
RXHCC
N/A—
Not mapped
Code Book Path
Inclusion Terms
OfficialICD-10-CM does not list inclusion terms for O43.021 in this effective period.
Excludes 2
OfficialICD-10-CM does not list Excludes 2 notes for O43.021 in this effective period.
Related Child Codes
Includes
OfficialICD-10-CM does not list Includes notes for O43.021 in this effective period.
Excludes 1
OfficialICD-10-CM does not list Excludes 1 notes for O43.021 in this effective period.
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for O43.021 in this effective period.
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for O43.021 in this effective period.
Code Also
OfficialICD-10-CM does not list Code Also instructions for O43.021 in this effective period.
Buddy Documentation Tip
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
Is O43.021 an HCC code?
No. O43.021 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.
- Code
- O43.021
- Description
- Fetus-to-fetus placental transfusion syndrome, first trimester
- HCC (V28)
- No CMS-HCC V28 mapping
- RAF
- —
- Billable
- Yes
- Payment year
- 2026
Coder workflow notes
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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
O43.021 is the ICD-10-CM diagnosis code for fetus-to-fetus placental transfusion syndrome, first trimester. An abnormal transfer of blood occurs between twins or multiples through a shared placenta during the first trimester of pregnancy. O43.021 sits in the ICD-10-CM chapter for pregnancy, childbirth and the puerperium (o00-o9a), within the section covering maternal care related to the fetus and amniotic cavity and possible delivery problems (o30-o48).
O43.021 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.
Confirm multiple gestation is documented before assigning this code.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for O43.021 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Confirm multiple gestation is documented before assigning this code
- •This condition is specific to monochorionic placentas shared by multiple fetuses

