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O43.021 ICD-10-CM Code: Fetus-to-fetus placental transfusion syndrome, first trimester

O43.021 is not a CMS-HCC payment code. MEAT criteria · RAF calculator · HCC Buddy coding tools

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FY 2026 Apr update / Pregnancy, childbirth and the puerperium (O00-O9A) / Maternal care related to the fetus and amniotic cavity and possible delivery problems (O30-O48)

O43.021

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Fetus-to-fetus placental transfusion syndrome, first trimester

An abnormal transfer of blood occurs between twins or multiples through a shared placenta during the first trimester of pregnancy.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

HCC 210

Varies by metal level

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
O43.0Placental transfusion syndromes
O43.02Fetus-to-fetus placental transfusion syndrome
O43.021Fetus-to-fetus placental transfusion syndrome, first trimester

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for O43.021 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for O43.021 in this effective period.

Related Child Codes

Official
O43.022Fetus-to-fetus placental transfusion syndrome, second trimester
O43.023Fetus-to-fetus placental transfusion syndrome, third trimester
O43.029Fetus-to-fetus placental transfusion syndrome, unspecified trimester

Includes

Official

ICD-10-CM does not list Includes notes for O43.021 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for O43.021 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for O43.021 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for O43.021 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for O43.021 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Confirm multiple gestation is documented before assigning this code
This condition is specific to monochorionic placentas shared by multiple fetuses

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is O43.021 an HCC code?

No. O43.021 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

Code
O43.021
Description
Fetus-to-fetus placental transfusion syndrome, first trimester
HCC (V28)
No CMS-HCC V28 mapping
RAF
Billable
Yes
Payment year
2026

Coder workflow notes

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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

O43.021 is the ICD-10-CM diagnosis code for fetus-to-fetus placental transfusion syndrome, first trimester. An abnormal transfer of blood occurs between twins or multiples through a shared placenta during the first trimester of pregnancy. O43.021 sits in the ICD-10-CM chapter for pregnancy, childbirth and the puerperium (o00-o9a), within the section covering maternal care related to the fetus and amniotic cavity and possible delivery problems (o30-o48).

O43.021 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Confirm multiple gestation is documented before assigning this code.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for O43.021 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Confirm multiple gestation is documented before assigning this code
  • This condition is specific to monochorionic placentas shared by multiple fetuses

Child Codes

Code Hierarchy

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