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M04 ICD-10-CM Code: Autoinflammatory syndromes

M04 is not a CMS-HCC payment code. MEAT criteria · RAF calculator · HCC coding software

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FY 2026 Apr update / Diseases of the musculoskeletal system and connective tissue (M00-M99) / Autoinflammatory syndromes (M04)

M04

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Autoinflammatory syndromes

Autoinflammatory syndromes

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
M0Autoinflammatory syndromes (M04)
M04Autoinflammatory syndromes

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for M04 in this effective period.

Excludes 2

Official
  • Crohn's disease (K50.-)

Related Child Codes

Official
M04.1Periodic fever syndromes
M04.2Cryopyrin-associated periodic syndromes
M04.8Other autoinflammatory syndromes
M04.9Autoinflammatory syndrome, unspecified

Includes

Official

ICD-10-CM does not list Includes notes for M04 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for M04 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for M04 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for M04 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for M04 in this effective period.

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Code
M04
Description
Autoinflammatory syndromes
HCC (V28)
No CMS-HCC V28 mapping
RAF
Billable
No
Payment year
2026

Coder workflow notes

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What This Code Means

M04 is the ICD-10-CM diagnosis code for autoinflammatory syndromes. M04 sits in the ICD-10-CM chapter for diseases of the musculoskeletal system and connective tissue (m00-m99), within the section covering autoinflammatory syndromes (m04).

Header codes like M04 cannot be reported on claims directly, they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at M04's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for M04 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Excludes 2, Not included here, may code separately

  • Crohn's disease (K50.-)

Child Codes

Code Hierarchy

M04Autoinflammatory syndromes
M04Autoinflammatory syndromes

M04 code history

Code setChange
FY2017 (effective Oct 1, 2016)Added to the code set

Source: official CMS ICD-10-CM order and addenda files, FY2016 through FY2027.

More on M04

Referenced in blog posts

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