What is ICD-10 code D72.110?

D72.110 is the ICD-10-CM diagnosis code for Idiopathic hypereosinophilic syndrome [IHES]. A rare disorder characterized by persistently elevated eosinophils in the blood that causes organ damage, with no identifiable secondary cause. D72.110 is a billable code, meaning it can be reported on a claim as a primary or secondary diagnosis when supported by documentation. D72.110 is part of the FY2026 ICD-10-CM code set published by the CMS National Center for Health Statistics and used on Medicare, Medicaid, and commercial claims in the United States.

Yes. D72.110 is a billable ICD-10-CM code that can be reported on professional and institutional claims as a primary or secondary diagnosis when the provider documentation supports the specific condition described. Billable codes in ICD-10-CM are coded to the highest level of specificity available for the documented diagnosis. D72.110 is current for fiscal year 2026 and remains in the active CMS ICD-10-CM code set published by the National Center for Health Statistics.

Which HCC does D72.110 map to under V28?

D72.110 has no payable CMS-HCC V28 mapping in the final FY2026 CMS file.

What RAF reference is published for D72.110?

D72.110 has no V28 reference coefficient because the final FY2026 source verifies no payable V28 mapping.

What is the V28 vs V24 difference for D72.110?

D72.110 has verified no payable V28 mapping in the final FY2026 source. Select a historical effective period before making any V24 comparison.

2026 ICD-10-CM D72.110: Idiopathic hypereosinophilic

D72.110 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · free HCC coding tools

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Code lookupD72.110

Effective periodFY2026 Apr Update (Apr 1-Sep 30)

FY 2026 Apr update / Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89) / Other disorders of blood and blood-forming organs (D70-D77)

D72.110

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Idiopathic hypereosinophilic syndrome [IHES]

A rare disorder characterized by persistently elevated eosinophils in the blood that causes organ damage, with no identifiable secondary cause.

Overview Risk Models Code Book Documentation Audit Notes Edition comparison

CMS-HCC V28

N/A

—

Not risk-adjusted for this model/period.

Not mapped

CMS-HCC V24

Historical

Not used for standard CY2026 Medicare Advantage payment. Select a historical period to review V24.

Not used for CY2026 payment

ACA/HHS

N/A

—

Not risk-adjusted for this model/period.

Not mapped

ESRD/PACE

N/A

—

Not risk-adjusted for this model/period.

Not mapped

RXHCC

N/A

—

Not risk-adjusted for this model/period.

Not mapped

Code Book Path

Official

D72.1Eosinophilia D72.11Hypereosinophilic syndrome [HES]D72.110Idiopathic hypereosinophilic syndrome [IHES]

Inclusion Terms

Official

No inclusion terms are included in this display for D72.110. Check the code and parent instructions in the Code Book.

Excludes 2

Official

autoimmune disease (systemic) NOS (M35.9)Inherited from D50-D89, D72, D72.1
certain conditions originating in the perinatal period (P00-P96)Inherited from D50-D89, D72, D72.1
complications of pregnancy, childbirth and the puerperium (O00-O9A)Inherited from D50-D89, D72, D72.1
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)Inherited from D50-D89, D72, D72.1
endocrine, nutritional and metabolic diseases (E00-E88)Inherited from D50-D89, D72, D72.1
human immunodeficiency virus [HIV] disease (B20)Inherited from D50-D89, D72, D72.1
injury, poisoning and certain other consequences of external causes (S00-T88)Inherited from D50-D89, D72, D72.1
neoplasms (C00-D49)Inherited from D50-D89, D72, D72.1
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)Inherited from D50-D89, D72, D72.1
neutropenia (D70)Inherited from D50-D89, D72, D72.1
Löffler's syndrome (J82.89)Inherited from D50-D89, D72, D72.1
pulmonary eosinophilia (J82.-)Inherited from D50-D89, D72, D72.1

Related Codes

Official

D72.111Lymphocytic Variant Hypereosinophilic Syndrome [LHES]D72.118Other hypereosinophilic syndrome D72.119Hypereosinophilic syndrome [HES], unspecified

Includes

Official

No Includes notes are included in this display for D72.110. Check the code and parent instructions in the Code Book.

Excludes 1

Official

basophilia (D72.824)Inherited from D72
immunity disorders (D80-D89)Inherited from D72
preleukemia (syndrome) (D46.9)Inherited from D72

Code First

Official

No Code First sequencing instructions are included in this display for D72.110. Check the code and parent instructions in the Code Book.

Use Additional

Official

No Use Additional Code instructions are included in this display for D72.110. Check the code and parent instructions in the Code Book.

Code Also

Official

No Code Also instructions are included in this display for D72.110. Check the code and parent instructions in the Code Book.

Buddy Documentation Tip

HCC Buddy guidance

IHES is a diagnosis of exclusion; ensure secondary causes of hypereosinophilia have been ruled out before coding this.

Document the organ systems involved and eosinophil count levels to support medical necessity.

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is D72.110 an HCC code?

No. D72.110 is a billable ICD-10-CM code with no mapping under the CMS-HCC V28 or V24 community payment models, and none under the ESRD, Part D RxHCC, or HHS-HCC models.

Code: D72.110
Description: Idiopathic hypereosinophilic syndrome [IHES]
HCC (V28): No CMS-HCC V28 mapping
RAF reference coefficient: —
Billable: Yes
Payment year: 2026

Coder workflow notes

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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

D72.110 is the ICD-10-CM diagnosis code for idiopathic hypereosinophilic syndrome [ihes]. A rare disorder characterized by persistently elevated eosinophils in the blood that causes organ damage, with no identifiable secondary cause. D72.110 sits in the ICD-10-CM chapter for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (d50-d89), within the section covering other disorders of blood and blood-forming organs (d70-d77).

D72.110 is a billable ICD-10-CM code, but the current payload does not show a mapping under the CMS-HCC V28 or V24 community payment models, and none under the ESRD, Part D RxHCC, or HHS-HCC models. Do not assign risk adjustment value from this page when no source-backed mapping is shown; verify the applicable model and payment year.

IHES is a diagnosis of exclusion; ensure secondary causes of hypereosinophilia have been ruled out before coding this.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for D72.110 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

•IHES is a diagnosis of exclusion; ensure secondary causes of hypereosinophilia have been ruled out before coding this.
•Document the organ systems involved and eosinophil count levels to support medical necessity.