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D48 ICD-10-CM Code: Neoplasm of uncertain behavior of other and unspecified sites

D48 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC Buddy coding tools

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Code lookupD48

FY 2026 Apr update / Neoplasms (C00-D49) / Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)

D48

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Neoplasm of uncertain behavior of other and unspecified sites

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Inclusion Terms

Official

No inclusion terms are included in this display for D48. Check the code and parent instructions in the Code Book.

Excludes 2

Official

No Excludes 2 notes are included in this display for D48. Check the code and parent instructions in the Code Book.

Includes

Official

No Includes notes are included in this display for D48. Check the code and parent instructions in the Code Book.

Excludes 1

Official
  • neurofibromatosis (nonmalignant) (Q85.0-)
  • neoplasms of unspecified behavior (D49.-)Inherited from D37-D48

Code First

Official

No Code First sequencing instructions are included in this display for D48. Check the code and parent instructions in the Code Book.

Use Additional

Official

No Use Additional Code instructions are included in this display for D48. Check the code and parent instructions in the Code Book.

Code Also

Official

No Code Also instructions are included in this display for D48. Check the code and parent instructions in the Code Book.

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Code
D48
Description
Neoplasm of uncertain behavior of other and unspecified sites
HCC (V28)
No CMS-HCC V28 mapping
RAF reference coefficient
Billable
No
Payment year
2026

Coder workflow notes

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What This Code Means

D48 is the ICD-10-CM diagnosis code for neoplasm of uncertain behavior of other and unspecified sites. D48 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (d37-d48).

Header codes like D48 cannot be reported on claims directly; they organize child codes that share clinical context. Coders should select the billable child code that matches the documented presentation and then verify its current source-backed HCC mapping. Do not infer a child code or risk adjustment value from the header alone.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for D48 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Excludes 1, Do NOT code together

  • neurofibromatosis (nonmalignant) (Q85.0-)

Child Codes

Code Hierarchy

D48Neoplasm of uncertain behavior of other and unspecified sites
D48Neoplasm of uncertain behavior of other and unspecified sites

More on D48

Referenced in blog posts

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