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D48.3 ICD-10-CM Code: Neoplasm of uncertain behavior of retroperitoneum

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FY 2026 Apr update / Neoplasms (C00-D49) / Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)

D48.3

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Neoplasm of uncertain behavior of retroperitoneum

A growth in the retroperitoneum (the space behind the abdominal cavity) that is not clearly cancer but has uncertain behavior.

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
D48Neoplasm of uncertain behavior of other and unspecified sites
D48.3Neoplasm of uncertain behavior of retroperitoneum

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for D48.3 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for D48.3 in this effective period.

Related Child Codes

Official
D48.0Neoplasm of uncertain behavior of bone and articular cartilage
D48.1Neoplasm of uncertain behavior of connective and other soft tissue
D48.2Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system
D48.4Neoplasm of uncertain behavior of peritoneum
D48.5Neoplasm of uncertain behavior of skin

Includes

Official

ICD-10-CM does not list Includes notes for D48.3 in this effective period.

Excludes 1

Official
  • neurofibromatosis (nonmalignant) (Q85.0-)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for D48.3 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for D48.3 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for D48.3 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Retroperitoneal tumors are often discovered incidentally on imaging; ensure the uncertain behavior is confirmed by pathology
Document the specific location within the retroperitoneum if possible for clinical clarity

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is D48.3 an HCC code?

No. D48.3 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

D48.3 is the ICD-10-CM diagnosis code for neoplasm of uncertain behavior of retroperitoneum. A growth in the retroperitoneum (the space behind the abdominal cavity) that is not clearly cancer but has uncertain behavior. D48.3 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (d37-d48).

D48.3 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Retroperitoneal tumors are often discovered incidentally on imaging; ensure the uncertain behavior is confirmed by pathology.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for D48.3 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Retroperitoneal tumors are often discovered incidentally on imaging; ensure the uncertain behavior is confirmed by pathology
  • Document the specific location within the retroperitoneum if possible for clinical clarity

Child Codes

Code Hierarchy

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