D46 ICD-10-CM Code: Myelodysplastic syndromes
D46 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC coding software
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FY 2026 Apr update / Neoplasms (C00-D49) / Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)
D46
Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidanceMyelodysplastic syndromes
CMS-HCC V28
N/A—
Not mapped
CMS-HCC V24
N/A—
Not mapped
ACA/HHS
N/A—
Not mapped
ESRD/PACE
N/A—
Not mapped
RXHCC
N/A—
Not mapped
Code Book Path
Inclusion Terms
OfficialNo inclusion terms are included in this display for D46. Check the code and parent instructions in the Code Book.
Excludes 2
Official- drug-induced aplastic anemia (D61.1)
Related Codes
Includes
OfficialNo Includes notes are included in this display for D46. Check the code and parent instructions in the Code Book.
Excludes 1
Official- neoplasms of unspecified behavior (D49.-)Inherited from D37-D48
Code First
OfficialNo Code First sequencing instructions are included in this display for D46. Check the code and parent instructions in the Code Book.
Use Additional
Official- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Code Also
OfficialNo Code Also instructions are included in this display for D46. Check the code and parent instructions in the Code Book.
Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →
- Code
- D46
- Description
- Myelodysplastic syndromes
- HCC (V28)
- No CMS-HCC V28 mapping
- RAF reference coefficient
- —
- Billable
- No
- Payment year
- 2026
Coder workflow notes
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What This Code Means
D46 is the ICD-10-CM diagnosis code for myelodysplastic syndromes. D46 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (d37-d48).
Header codes like D46 cannot be reported on claims directly; they organize child codes that share clinical context. Coders should select the billable child code that matches the documented presentation and then verify its current source-backed HCC mapping. Do not infer a child code or risk adjustment value from the header alone.
HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for D46 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Excludes 2, Not included here, may code separately
- drug-induced aplastic anemia (D61.1)