FY2027 ICD-10-CM reference
T80: Complications following infusion, transfusion and therapeutic injection
By the HCC Buddy Coding Team
The official ICD-10-CM descriptor is Complications following infusion, transfusion and therapeutic injection. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Nonbillable heading. Verified against the official FY2027 order file.
CMS-HCC V28
Not applicable to this nonbillable heading
CMS-HCC V24
Not applicable to this nonbillable heading
ESRD
Not applicable to this nonbillable heading
PACE
Not applicable to this nonbillable heading
RxHCC
Not applicable to this nonbillable heading
HHS-HCC
Not applicable to this nonbillable heading
More specific FY2027 codes
- T80.0: Air embolism following infusion, transfusion and therapeutic injectionNonbillable heading
- T80.1: Vascular complications following infusion, transfusion and therapeutic injectionNonbillable heading
- T80.2: Infections following infusion, transfusion and therapeutic injectionNonbillable heading
- T80.3: ABO incompatibility reaction due to transfusion of blood or blood productsNonbillable heading
- T80.4: Rh incompatibility reaction due to transfusion of blood or blood productsNonbillable heading
- T80.A: Non-ABO incompatibility reaction due to transfusion of blood or blood productsNonbillable heading
- T80.5: Anaphylactic reaction due to serumNonbillable heading
- T80.6: Other serum reactionsNonbillable heading
- T80.8: Other complications following infusion, transfusion and therapeutic injectionNonbillable heading
- T80.9: Unspecified complication following infusion, transfusion and therapeutic injectionNonbillable heading
FY2027 Tabular instructions
Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.
Instructional note
Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
Source: S00-T88 (chapter, inherited).
Instructional note
code to identify any retained foreign body, if applicable (Z18.-)
Source: S00-T88 (chapter, inherited).
Excludes2
birth trauma (P10-P15)
Source: S00-T88 (chapter, inherited).
Excludes2
obstetric trauma (O70-O71)
Source: S00-T88 (chapter, inherited).
Instructional note
The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.
Source: S00-T88 (chapter, inherited).
Instructional note
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Source: T80-T88 (section, inherited).
Instructional note
code(s) to identify the specified condition resulting from the complication
Source: T80-T88 (section, inherited).
Instructional note
code to identify devices involved and details of circumstances (Y62-Y82)
Source: T80-T88 (section, inherited).
Excludes2
any encounters with medical care for postprocedural conditions in which no complications are present, such as:
Source: T80-T88 (section, inherited).
Excludes2
artificial opening status (Z93.-)
Source: T80-T88 (section, inherited).
Excludes2
closure of external stoma (Z43.-)
Source: T80-T88 (section, inherited).
Excludes2
fitting and adjustment of external prosthetic device (Z44.-)
Source: T80-T88 (section, inherited).
Excludes2
burns and corrosions from local applications and irradiation (T20-T32)
Source: T80-T88 (section, inherited).
Excludes2
complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
Source: T80-T88 (section, inherited).
Excludes2
mechanical complication of respirator [ventilator] (J95.850)
Source: T80-T88 (section, inherited).
Excludes2
poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
Source: T80-T88 (section, inherited).
Excludes2
postprocedural fever (R50.82)
Source: T80-T88 (section, inherited).
Excludes2
specified complications classified elsewhere, such as:
Source: T80-T88 (section, inherited).
Excludes2
cerebrospinal fluid leak from spinal puncture (G97.0)
Source: T80-T88 (section, inherited).
Excludes2
colostomy malfunction (K94.0-)
Source: T80-T88 (section, inherited).
Excludes2
disorders of fluid and electrolyte imbalance (E86-E87)
Source: T80-T88 (section, inherited).
Excludes2
functional disturbances following cardiac surgery (I97.0-I97.1)
Source: T80-T88 (section, inherited).
Excludes2
intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
Source: T80-T88 (section, inherited).
Excludes2
ostomy complications (J95.0-, K94.-, N99.5-)
Source: T80-T88 (section, inherited).
Excludes2
postgastric surgery syndromes (K91.1)
Source: T80-T88 (section, inherited).
Excludes2
postlaminectomy syndrome NEC (M96.1)
Source: T80-T88 (section, inherited).
Excludes2
postmastectomy lymphedema syndrome (I97.2)
Source: T80-T88 (section, inherited).
Excludes2
postsurgical blind-loop syndrome (K91.2)
Source: T80-T88 (section, inherited).
Excludes2
ventilator associated pneumonia (J95.851)
Source: T80-T88 (section, inherited).
Includes
complications following perfusion
Source: T80 (category, direct).
Excludes2
bone marrow transplant rejection (T86.01)
Source: T80 (category, direct).
Excludes2
febrile nonhemolytic transfusion reaction (R50.84)
Source: T80 (category, direct).
Excludes2
fluid overload due to transfusion (E87.71)
Source: T80 (category, direct).
Excludes2
posttransfusion purpura (D69.51)
Source: T80 (category, direct).
Excludes2
transfusion associated circulatory overload (TACO) (E87.71)
Source: T80 (category, direct).
Excludes2
transfusion (red blood cell) associated hemochromatosis (E83.111)
Source: T80 (category, direct).
Excludes2
transfusion related acute lung injury (TRALI) (J95.84)
Source: T80 (category, direct).
Seventh-character instruction
The appropriate 7th character is to be added to each code from category T80
Source: T80 (category, direct).
Instructional note
initial encounter
Source: T80 (category, direct).
Instructional note
subsequent encounter
Source: T80 (category, direct).
Instructional note
sequela
Source: T80 (category, direct).
Seventh-character definitions
- A: initial encounter
- D: subsequent encounter
- S: sequela
Compare the FY2027 additions, removals and billable-status changes
What does T80 mean in FY2027?
The official ICD-10-CM descriptor is Complications following infusion, transfusion and therapeutic injection. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Is T80 billable in FY2027?
The FY2027 order file marks T80 as a nonbillable heading. Select a complete billable child code.
Does T80 map to an HCC?
Risk-model mapping is not applicable to this nonbillable heading. Check a complete billable child code.
Source: CMS FY2027 ICD-10-CM order file. Payment model: CMS CY 2027 Rate Announcement. Read the FY2027 Official Guidelines.
Review the FY2026 April edition
