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T80 ICD-10-CM Code: Complications following infusion, transfusion and therapeutic injection

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FY 2026 Apr update / Injury, poisoning and certain other consequences of external causes (S00-T88) / Complications of surgical and medical care, not elsewhere classified (T80-T88)

T80

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Complications following infusion, transfusion and therapeutic injection

Complications following infusion, transfusion and therapeutic injection

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
T8Complications of surgical and medical care, not elsewhere classified (T80-T88)
T80Complications following infusion, transfusion and therapeutic injection

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for T80 in this effective period.

Excludes 2

Official
  • bone marrow transplant rejection (T86.01)
  • febrile nonhemolytic transfusion reaction (R50.84)
  • fluid overload due to transfusion (E87.71)
  • posttransfusion purpura (D69.51)
  • transfusion associated circulatory overload (TACO) (E87.71)

Related Child Codes

Official
T80.0Air embolism following infusion, transfusion and therapeutic injection
T80.1Vascular complications following infusion, transfusion and therapeutic injection
T80.2Infections following infusion, transfusion and therapeutic injection
T80.3ABO incompatibility reaction due to transfusion of blood or blood products
T80.4Rh incompatibility reaction due to transfusion of blood or blood products

Includes

Official
  • complications following perfusion

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for T80 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for T80 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for T80 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for T80 in this effective period.

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Coder workflow notes

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What This Code Means

T80 is the ICD-10-CM diagnosis code for complications following infusion, transfusion and therapeutic injection. T80 sits in the ICD-10-CM chapter for injury, poisoning and certain other consequences of external causes (s00-t88), within the section covering complications of surgical and medical care, not elsewhere classified (t80-t88).

Header codes like T80 cannot be reported on claims directly, they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at T80's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for T80 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Includes

  • complications following perfusion

Excludes 2, Not included here, may code separately

  • bone marrow transplant rejection (T86.01)
  • febrile nonhemolytic transfusion reaction (R50.84)
  • fluid overload due to transfusion (E87.71)
  • posttransfusion purpura (D69.51)
  • transfusion associated circulatory overload (TACO) (E87.71)
  • transfusion (red blood cell) associated hemochromatosis (E83.111)
  • transfusion related acute lung injury (TRALI) (J95.84)

Child Codes

Code Hierarchy

T80Complications following infusion, transfusion and therapeutic injection
T80Complications following infusion, transfusion and therapeutic injection

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