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F33 ICD-10-CM Code: Major depressive disorder, recurrent

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FY 2026 Apr update / Mental, Behavioral and Neurodevelopmental disorders (F01-F99) / Mood [affective] disorders (F30-F39)

F33

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Major depressive disorder, recurrent

Major depressive disorder, recurrent

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
F3Mood [affective] disorders (F30-F39)
F33Major depressive disorder, recurrent

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for F33 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for F33 in this effective period.

Related Child Codes

Official
F33.0Major depressive disorder, recurrent, mild
F33.1Major depressive disorder, recurrent, moderate
F33.2Major depressive disorder, recurrent severe without psychotic features
F33.3Major depressive disorder, recurrent, severe with psychotic symptoms
F33.4Major depressive disorder, recurrent, in remission

Includes

Official
  • recurrent episodes of depressive reaction
  • recurrent episodes of endogenous depression
  • recurrent episodes of major depression
  • recurrent episodes of psychogenic depression
  • recurrent episodes of reactive depression

Excludes 1

Official
  • bipolar disorder (F31.-)
  • manic episode (F30.-)

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for F33 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for F33 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for F33 in this effective period.

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Coder workflow notes

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What This Code Means

F33 is the ICD-10-CM diagnosis code for major depressive disorder, recurrent. F33 sits in the ICD-10-CM chapter for mental, behavioral and neurodevelopmental disorders (f01-f99), within the section covering mood [affective] disorders (f30-f39).

Header codes like F33 cannot be reported on claims directly, they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at F33's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for F33 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Includes

  • recurrent episodes of depressive reaction
  • recurrent episodes of endogenous depression
  • recurrent episodes of major depression
  • recurrent episodes of psychogenic depression
  • recurrent episodes of reactive depression
  • recurrent episodes of seasonal affective disorder
  • recurrent episodes of seasonal depressive disorder
  • recurrent episodes of vital depression

Excludes 1, Do NOT code together

  • bipolar disorder (F31.-)
  • manic episode (F30.-)

Child Codes

Code Hierarchy

F33Major depressive disorder, recurrent
F33Major depressive disorder, recurrent

More on F33

Related condition guides

Referenced in blog posts

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