FY2027 ICD-10-CM reference
E72: Other disorders of amino-acid metabolism
By the HCC Buddy Coding Team
The official ICD-10-CM descriptor is Other disorders of amino-acid metabolism. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Nonbillable heading. Verified against the official FY2027 order file.
CMS-HCC V28
Not applicable to this nonbillable heading
CMS-HCC V24
Not applicable to this nonbillable heading
ESRD
Not applicable to this nonbillable heading
PACE
Not applicable to this nonbillable heading
RxHCC
Not applicable to this nonbillable heading
HHS-HCC
Not applicable to this nonbillable heading
More specific FY2027 codes
- E72.0: Disorders of amino-acid transportNonbillable heading
- E72.1: Disorders of sulfur-bearing amino-acid metabolismNonbillable heading
- E72.2: Disorders of urea cycle metabolismNonbillable heading
- E72.3: Disorders of lysine and hydroxylysine metabolismBillable code
- E72.4: Disorders of ornithine metabolismBillable code
- E72.5: Disorders of glycine metabolismNonbillable heading
- E72.8: Other specified disorders of amino-acid metabolismNonbillable heading
- E72.9: Disorder of amino-acid metabolism, unspecifiedBillable code
FY2027 Tabular instructions
Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.
Instructional note
All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Source: E00-E89 (chapter, inherited).
Excludes1
transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Source: E00-E89 (chapter, inherited).
Excludes1
androgen insensitivity syndrome (E34.5-)
Source: E70-E88 (section, inherited).
Excludes1
congenital adrenal hyperplasia (E25.0)
Source: E70-E88 (section, inherited).
Excludes1
hemolytic anemias attributable to enzyme disorders (D55.-)
Source: E70-E88 (section, inherited).
Excludes1
Marfan syndrome (Q87.4-)
Source: E70-E88 (section, inherited).
Excludes1
5-alpha-reductase deficiency (E29.1)
Source: E70-E88 (section, inherited).
Excludes2
Ehlers-Danlos syndromes (Q79.6-)
Source: E70-E88 (section, inherited).
Excludes1
disorders of:
Source: E72 (category, direct).
Excludes1
aromatic amino-acid metabolism (E70.-)
Source: E72 (category, direct).
Excludes1
branched-chain amino-acid metabolism (E71.0-E71.2)
Source: E72 (category, direct).
Excludes1
fatty-acid metabolism (E71.3)
Source: E72 (category, direct).
Excludes1
purine and pyrimidine metabolism (E79.-)
Source: E72 (category, direct).
Excludes1
gout (M1A.-, M10.-)
Source: E72 (category, direct).
Compare the FY2027 additions, removals and billable-status changes
What does E72 mean in FY2027?
The official ICD-10-CM descriptor is Other disorders of amino-acid metabolism. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Is E72 billable in FY2027?
The FY2027 order file marks E72 as a nonbillable heading. Select a complete billable child code.
Does E72 map to an HCC?
Risk-model mapping is not applicable to this nonbillable heading. Check a complete billable child code.
Source: CMS FY2027 ICD-10-CM order file. Payment model: CMS CY 2027 Rate Announcement. Read the FY2027 Official Guidelines.
Review the FY2026 April edition