FY2027 ICD-10-CM reference
E27.1: Primary adrenocortical insufficiency
By the HCC Buddy Coding Team
The official ICD-10-CM descriptor is Primary adrenocortical insufficiency. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Billable code. Verified against the official FY2027 order file.
FY2027 Tabular instructions
Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.
Instructional note
All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Source: E00-E89 (chapter, inherited).
Excludes1
transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Source: E00-E89 (chapter, inherited).
Excludes1
galactorrhea (N64.3)
Source: E20-E35 (section, inherited).
Excludes1
gynecomastia (N62)
Source: E20-E35 (section, inherited).
Instructional note
Addison's disease
Source: E27.1 (self, direct).
Instructional note
Autoimmune adrenalitis
Source: E27.1 (self, direct).
Excludes1
Addison only phenotype adrenoleukodystrophy (E71.528)
Source: E27.1 (self, direct).
Excludes1
amyloidosis (E85.-)
Source: E27.1 (self, direct).
Excludes1
tuberculous Addison's disease (A18.7)
Source: E27.1 (self, direct).
Excludes1
Waterhouse-Friderichsen syndrome (A39.1)
Source: E27.1 (self, direct).
Compare the FY2027 additions, removals and billable-status changes
What does E27.1 mean in FY2027?
The official ICD-10-CM descriptor is Primary adrenocortical insufficiency. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Is E27.1 billable in FY2027?
The FY2027 order file marks E27.1 as billable. Check the complete Tabular instructions and documentation before assigning it.
Does E27.1 map to an HCC?
HCC mapping verification is pending for this edition. No HCC category or RAF coefficient is shown.
Source: CMS FY2027 ICD-10-CM order file. Read the FY2027 Official Guidelines.
Review the FY2026 April edition
