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FY2027 ICD-10-CM reference

E27.1: Primary adrenocortical insufficiency

By the HCC Buddy Coding Team

The official ICD-10-CM descriptor is Primary adrenocortical insufficiency. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.

Billable code. Verified against the official FY2027 order file.

CMS-HCC V28

Source verification pending

CMS-HCC V24

Source verification pending

ESRD

Source verification pending

PACE

Source verification pending

RxHCC

Source verification pending

HHS-HCC

Source verification pending

FY2027 Tabular instructions

Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.

Instructional note

All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: E00-E89 (chapter, inherited).

Excludes1

transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Source: E00-E89 (chapter, inherited).

Excludes1

galactorrhea (N64.3)

Source: E20-E35 (section, inherited).

Excludes1

gynecomastia (N62)

Source: E20-E35 (section, inherited).

Instructional note

Addison's disease

Source: E27.1 (self, direct).

Instructional note

Autoimmune adrenalitis

Source: E27.1 (self, direct).

Excludes1

Addison only phenotype adrenoleukodystrophy (E71.528)

Source: E27.1 (self, direct).

Excludes1

amyloidosis (E85.-)

Source: E27.1 (self, direct).

Excludes1

tuberculous Addison's disease (A18.7)

Source: E27.1 (self, direct).

Excludes1

Waterhouse-Friderichsen syndrome (A39.1)

Source: E27.1 (self, direct).

Source: CMS FY2027 Tabular List and Alphabetic Index.

Open Tabular instructions and code details

Compare the FY2027 additions, removals and billable-status changes

What does E27.1 mean in FY2027?

The official ICD-10-CM descriptor is Primary adrenocortical insufficiency. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.

Is E27.1 billable in FY2027?

The FY2027 order file marks E27.1 as billable. Check the complete Tabular instructions and documentation before assigning it.

Does E27.1 map to an HCC?

HCC mapping verification is pending for this edition. No HCC category or RAF coefficient is shown.

Source: CMS FY2027 ICD-10-CM order file. Read the FY2027 Official Guidelines.

Review the FY2026 April edition