FY2027 ICD-10-CM reference
D56.2: Delta-beta thalassemia
By the HCC Buddy Coding Team
The official ICD-10-CM descriptor is Delta-beta thalassemia. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Billable code. Verified against the official FY2027 order file.
FY2027 Tabular instructions
Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.
Excludes2
autoimmune disease (systemic) NOS (M35.9)
Source: D50-D89 (chapter, inherited).
Excludes2
certain conditions originating in the perinatal period (P00-P96)
Source: D50-D89 (chapter, inherited).
Excludes2
complications of pregnancy, childbirth and the puerperium (O00-O9A)
Source: D50-D89 (chapter, inherited).
Excludes2
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
Source: D50-D89 (chapter, inherited).
Excludes2
endocrine, nutritional and metabolic diseases (E00-E88)
Source: D50-D89 (chapter, inherited).
Excludes2
human immunodeficiency virus [HIV] disease (B20)
Source: D50-D89 (chapter, inherited).
Excludes2
injury, poisoning and certain other consequences of external causes (S00-T88)
Source: D50-D89 (chapter, inherited).
Excludes2
neoplasms (C00-D49)
Source: D50-D89 (chapter, inherited).
Excludes2
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Source: D50-D89 (chapter, inherited).
Excludes1
sickle-cell thalassemia (D57.4-)
Source: D56 (category, inherited).
Instructional note
Homozygous delta-beta thalassemia
Source: D56.2 (self, direct).
Excludes1
delta-beta thalassemia minor (D56.3)
Source: D56.2 (self, direct).
Excludes1
delta-beta thalassemia trait (D56.3)
Source: D56.2 (self, direct).
Compare the FY2027 additions, removals and billable-status changes
What does D56.2 mean in FY2027?
The official ICD-10-CM descriptor is Delta-beta thalassemia. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Is D56.2 billable in FY2027?
The FY2027 order file marks D56.2 as billable. Check the complete Tabular instructions and documentation before assigning it.
Does D56.2 map to an HCC?
HCC mapping verification is pending for this edition. No HCC category or RAF coefficient is shown.
Source: CMS FY2027 ICD-10-CM order file. Read the FY2027 Official Guidelines.
Review the FY2026 April edition