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C78

Non-Billable (Header)

Secondary malignant neoplasm of respiratory and digestive organs

Last updated: FY2026 ICD-10-CM (Oct 1, 2025 – Sep 30, 2026) | CMS-HCC V28 (100% phase-in, PY2026)

What This Code Means

C78 is the ICD-10-CM diagnosis code for secondary malignant neoplasm of respiratory and digestive organs. C78 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of ill-defined, other secondary and unspecified sites (c76-c80).

Header codes like C78 cannot be reported on claims directly — they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at C78's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for C78 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Excludes 1 — Do NOT code together

  • secondary carcinoid tumors of liver (C7B.02)
  • secondary carcinoid tumors of peritoneum (C7B.04)

Excludes 2 — Not included here, may code separately

  • lymph node metastases (C77.0)

Child Codes

Code Hierarchy

C78Secondary malignant neoplasm of respiratory and digestive organs
C78Secondary malignant neoplasm of respiratory and digestive organs

More on C78

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