FY2027 ICD-10-CM reference
A41.1: Sepsis due to other specified staphylococcus
By the HCC Buddy Coding Team
The official ICD-10-CM descriptor is Sepsis due to other specified staphylococcus. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Billable code. Verified against the official FY2027 order file.
FY2027 Tabular instructions
Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.
Includes
diseases generally recognized as communicable or transmissible
Source: A00-B99 (chapter, inherited).
Instructional note
code to identify resistance to antimicrobial drugs (Z16.-)
Source: A00-B99 (chapter, inherited).
Excludes2
carrier or suspected carrier of infectious disease (Z22.-)
Source: A00-B99 (chapter, inherited).
Excludes2
certain localized infections - see body system-related chapters
Source: A00-B99 (chapter, inherited).
Excludes2
infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
Source: A00-B99 (chapter, inherited).
Excludes2
infectious and parasitic diseases specific to the perinatal period (P35-P39)
Source: A00-B99 (chapter, inherited).
Excludes2
influenza and other acute respiratory infections (J00-J22)
Source: A00-B99 (chapter, inherited).
Code first
, if applicable, postprocedural sepsis (T81.44-)
Source: A41 (category, inherited).
Code first
sepsis due to central venous catheter (T80.211-)
Source: A41 (category, inherited).
Code first
sepsis during labor (O75.3)
Source: A41 (category, inherited).
Code first
sepsis following abortion, ectopic or molar pregnancy (O03.37, O03.87, O04.87, O07.37, O08.82)
Source: A41 (category, inherited).
Code first
sepsis following immunization (T88.0-)
Source: A41 (category, inherited).
Code first
sepsis following infusion, transfusion or therapeutic injection (T80.22-, T80.29-)
Source: A41 (category, inherited).
Excludes1
bacteremia NOS (R78.81)
Source: A41 (category, inherited).
Excludes1
neonatal (P36.-)
Source: A41 (category, inherited).
Excludes1
puerperal sepsis (O85)
Source: A41 (category, inherited).
Excludes1
streptococcal sepsis (A40.-)
Source: A41 (category, inherited).
Excludes2
sepsis (due to) (in) actinomycotic (A42.7)
Source: A41 (category, inherited).
Excludes2
sepsis (due to) (in) anthrax (A22.7)
Source: A41 (category, inherited).
Excludes2
sepsis (due to) (in) candidal (B37.7)
Source: A41 (category, inherited).
Excludes2
sepsis (due to) (in) Erysipelothrix (A26.7)
Source: A41 (category, inherited).
Excludes2
sepsis (due to) (in) extraintestinal yersiniosis (A28.2)
Source: A41 (category, inherited).
Excludes2
sepsis (due to) (in) gonococcal (A54.86)
Source: A41 (category, inherited).
Excludes2
sepsis (due to) (in) herpesviral (B00.7)
Source: A41 (category, inherited).
Excludes2
sepsis (due to) (in) listerial (A32.7)
Source: A41 (category, inherited).
Excludes2
sepsis (due to) (in) melioidosis (A24.1)
Source: A41 (category, inherited).
Excludes2
sepsis (due to) (in) meningococcal (A39.2-A39.4)
Source: A41 (category, inherited).
Excludes2
sepsis (due to) (in) plague (A20.7)
Source: A41 (category, inherited).
Excludes2
sepsis (due to) (in) tularemia (A21.7)
Source: A41 (category, inherited).
Excludes2
toxic shock syndrome (A48.3)
Source: A41 (category, inherited).
Instructional note
Coagulase negative staphylococcus sepsis
Source: A41.1 (self, direct).
Compare the FY2027 additions, removals and billable-status changes
What does A41.1 mean in FY2027?
The official ICD-10-CM descriptor is Sepsis due to other specified staphylococcus. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Is A41.1 billable in FY2027?
The FY2027 order file marks A41.1 as billable. Check the complete Tabular instructions and documentation before assigning it.
Does A41.1 map to an HCC?
In the CMS 2027 Initial ICD-10-CM Mappings (payment year 2027, 2026 dates of service), A41.1 maps to CMS-HCC V28 HCC 2 (Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock). For 2027 dates of service, CMS has not yet published the payment year 2028 mappings. ESRD, RxHCC, PACE and HHS-HCC mappings are still pending verification for FY2027.
Source: CMS FY2027 ICD-10-CM order file. Read the FY2027 Official Guidelines.
Review the FY2026 April edition