New for FY2027 ICD-10-CM · October 1, 2026
QA1.791: Familial cancer syndrome with pathogenic BRCA2 mutation
By the HCC Buddy Coding Team
The official ICD-10-CM descriptor is Familial cancer syndrome with pathogenic BRCA2 mutation. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
Billable code. Verified against the official FY2027 order file.
FY2027 Tabular instructions
Instructions below include applicable chapter, section and parent-code notes. Each note identifies where it appears in the official source.
Instructional note
Codes from this chapter are not for use on maternal records
Source: Q00-QA1 (chapter, inherited).
Excludes2
inborn errors of metabolism (E70-E88)
Source: Q00-QA1 (chapter, inherited).
Code also
, if applicable, any associated conditions, such as:
Source: QA1 (category, inherited).
Code also
genetic susceptibility to malignant neoplasm by site (Z15.0-)
Source: QA1 (category, inherited).
Code also
malignant neoplasms (C00.0-C96.9)
Source: QA1 (category, inherited).
Code also
personal history of malignant neoplasm (Z85.-)
Source: QA1 (category, inherited).
Excludes2
multiple endocrine neoplasia [MEN] syndromes (E31.2-)
Source: QA1 (category, inherited).
Instructional note
BRCA2-cancer predisposition syndrome
Source: QA1.791 (self, direct).
Instructional note
Hereditary breast and ovarian cancer syndrome with pathogenic BRCA2 mutation
Source: QA1.791 (self, direct).
Compare the FY2027 additions, removals and billable-status changes
What does QA1.791 mean in FY2027?
The official ICD-10-CM descriptor is Familial cancer syndrome with pathogenic BRCA2 mutation. The FY2027 annual edition starts October 1, 2026. Check the edition that applies to the encounter or inpatient discharge, including any April update.
When did QA1.791 become an ICD-10-CM code?
QA1.791 is new for FY2027 ICD-10-CM, effective October 1, 2026. It is absent from the FY2026 April order file. Use the code set that applies to the encounter or inpatient discharge date, and check the official Tabular instructions.
Is QA1.791 billable in FY2027?
The FY2027 order file marks QA1.791 as billable. Check the complete Tabular instructions and documentation before assigning it.
Does QA1.791 map to an HCC?
QA1.791 is not in the current CMS mapping file (it is new for FY2027), and CMS has not yet published payment year 2028 mappings. No HCC category or RAF coefficient is shown.
Source: CMS FY2027 ICD-10-CM order file. Payment model: CMS CY 2027 Rate Announcement. Read the FY2027 Official Guidelines.