QA0.0149 ICD-10-CM Code: Neurodevelopmental disorder, related to pathogenic variant in other synapse related gene
HCC Buddy Code Card
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FY 2026 Apr update / Congenital malformations, deformations and chromosomal abnormalities (Q00-QA0) / Genetic disorders, not elsewhere classified (QA0)
QA0.0149
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceNeurodevelopmental disorder, related to pathogenic variant in other synapse related gene
A developmental disorder affecting brain and nervous system function caused by a genetic change in genes that help nerve cells communicate with each other.
CMS-HCC V28
N/A—
Not mapped
CMS-HCC V24
N/A—
Not mapped
ACA/HHS
MappedHCC 97
Varies by metal level
ESRD/PACE
N/A—
Not mapped
RXHCC
N/A—
Not mapped
Code Book Path
Inclusion Terms
Official- Other genetic synaptopathy
Excludes 2
OfficialICD-10-CM does not list Excludes 2 notes for QA0.0149 in this effective period.
Related Child Codes
Includes
OfficialICD-10-CM does not list Includes notes for QA0.0149 in this effective period.
Excludes 1
OfficialICD-10-CM does not list Excludes 1 notes for QA0.0149 in this effective period.
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for QA0.0149 in this effective period.
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for QA0.0149 in this effective period.
Code Also
OfficialICD-10-CM does not list Code Also instructions for QA0.0149 in this effective period.
Buddy Documentation Tip
Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.
Is QA0.0149 an HCC code?
No. QA0.0149 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.
Coder workflow notes
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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
QA0.0149 is the ICD-10-CM diagnosis code for neurodevelopmental disorder, related to pathogenic variant in other synapse related gene. A developmental disorder affecting brain and nervous system function caused by a genetic change in genes that help nerve cells communicate with each other. QA0.0149 sits in the ICD-10-CM chapter for congenital malformations, deformations and chromosomal abnormalities (q00-qa0), within the section covering genetic disorders, not elsewhere classified (qa0).
QA0.0149 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.
Requires documentation of the specific synapse-related gene involved when available.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for QA0.0149 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Requires documentation of the specific synapse-related gene involved when available
- •Use this code when the pathogenic variant is identified but doesn't fit other more specific neurodevelopmental disorder codes