Question 1

What is ICD-10 code QA0.0141?

Accepted Answer

QA0.0141 is the ICD-10-CM diagnosis code for syntaxin-binding protein 1-related disorder. A neurodevelopmental disorder caused by mutations in the STXBP1 gene, which affects how nerve cells release neurotransmitters and can cause seizures, developmental delays, and movement problems. QA0.0141 sits in the ICD-10-CM chapter for congenital malformations, deformations and chromosomal abnormalities (q00-qa0), within the section covering genetic disorders, not elsewhere classified (qa0).

QA0.0141 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Confirm genetic testing documentation for STXBP1 pathogenic variant.

Question 2

Is QA0.0141 an HCC code?

Accepted Answer

No. QA0.0141 is a billable ICD-10-CM code but does not map to any payment HCC category under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can still be reported on Medicare Advantage encounter data submissions, but it does not contribute to the beneficiary's Risk Adjustment Factor (RAF) score and therefore does not affect the risk-adjusted capitation payment to the plan. V28 reached 100% phase-in for payment year 2026.

Question 3

Is QA0.0141 billable?

Accepted Answer

Yes. QA0.0141 is a billable ICD-10-CM code that can be reported on professional and institutional claims as a primary or secondary diagnosis when the provider documentation supports the specific condition described. Billable codes in ICD-10-CM are coded to the highest level of specificity available for the documented diagnosis. QA0.0141 is current for fiscal year 2026 and remains in the active CMS ICD-10-CM code set published by the National Center for Health Statistics.

Question 4

What is the V28 vs V24 difference for QA0.0141?

Accepted Answer

QA0.0141 does not map to a payment HCC under either the CMS-HCC V28 risk adjustment model or the older V24 model. V28 reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition. Because neither model rewards QA0.0141 with a risk adjustment factor, it contributes zero to a Medicare Advantage beneficiary's RAF score in either version. Coders should check whether provider documentation supports a more specific child code that does map to a payment HCC.

Question 5

What should coders know when reporting QA0.0141?

Accepted Answer

Confirm genetic testing documentation for STXBP1 pathogenic variant Code associated seizure disorder and developmental manifestations with additional codes

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QA0.0141

Is QA0.0141 an HCC code?

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QA0.0141 ICD-10-CM Code: Syntaxin-binding protein 1-related disorder

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QA0.0141

Is QA0.0141 an HCC code?

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What This Code Means

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