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T50.915S ICD-10-CM Code: Adverse effect of multiple unspecified drugs, medicaments and biological substances, sequela

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FY 2026 Apr update / Injury, poisoning and certain other consequences of external causes (S00-T88) / Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50)

T50.915S

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Adverse effect of multiple unspecified drugs, medicaments and biological substances, sequela

Adverse effect of multiple unspecified drugs, medicaments and biological substances, sequela

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
T50.91Poisoning by, adverse effect of and underdosing of multiple unspecified drugs, medicaments and biological substances
T50.915Adverse effect of multiple unspecified drugs, medicaments and biological substances
T50.915SAdverse effect of multiple unspecified drugs, medicaments and biological substances, sequela

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for T50.915S in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for T50.915S in this effective period.

Related Child Codes

Official
T50.915AAdverse effect of multiple unspecified drugs, medicaments and biological substances, initial encounter
T50.915DAdverse effect of multiple unspecified drugs, medicaments and biological substances, subsequent encounter

Includes

Official

ICD-10-CM does not list Includes notes for T50.915S in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for T50.915S in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for T50.915S in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for T50.915S in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for T50.915S in this effective period.

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is T50.915S an HCC code?

No. T50.915S is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

T50.915S is the ICD-10-CM diagnosis code for adverse effect of multiple unspecified drugs, medicaments and biological substances, sequela. T50.915S sits in the ICD-10-CM chapter for injury, poisoning and certain other consequences of external causes (s00-t88), within the section covering poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (t36-t50).

T50.915S is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

T50.915S is a billable ICD-10-CM code that can be reported on claims but does not currently contribute to a Medicare Advantage member's RAF score under any CMS risk adjustment model (V28, V24, ESRD, or RxHCC). Coders reviewing T50.915S should check whether additional documentation would support a more specific child code in the same hierarchy that does map to a payment HCC, capturing the correct specificity is the highest-impact RAF improvement available within accurate coding.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for T50.915S sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Child Codes

Code Hierarchy

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