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G92.0 ICD-10-CM Code: Immune effector cell-associated neurotoxicity syndrome

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FY 2026 Apr update / Diseases of the nervous system (G00-G99) / Other disorders of the nervous system (G89-G99)

G92.0

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Immune effector cell-associated neurotoxicity syndrome

Immune effector cell-associated neurotoxicity syndrome

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

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Code Book Path

Official
G92Toxic encephalopathy
G92.0Immune effector cell-associated neurotoxicity syndrome

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for G92.0 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for G92.0 in this effective period.

Related Child Codes

Official
G92.00Immune effector cell-associated neurotoxicity syndrome, grade unspecified
G92.01Immune effector cell-associated neurotoxicity syndrome, grade 1
G92.02Immune effector cell-associated neurotoxicity syndrome, grade 2
G92.03Immune effector cell-associated neurotoxicity syndrome, grade 3
G92.04Immune effector cell-associated neurotoxicity syndrome, grade 4

Includes

Official

ICD-10-CM does not list Includes notes for G92.0 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for G92.0 in this effective period.

Code First

Official
  • underlying cause such as:
  • complications of immune effector cellular therapy (T80.82)

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for G92.0 in this effective period.

Code Also

Official
  • , if applicable, associated signs and symptoms, such as:
  • cerebral edema (G93.6)
  • unspecified convulsions (R56.9)

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Coder workflow notes

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What This Code Means

G92.0 is the ICD-10-CM diagnosis code for immune effector cell-associated neurotoxicity syndrome. G92.0 sits in the ICD-10-CM chapter for diseases of the nervous system (g00-g99), within the section covering other disorders of the nervous system (g89-g99).

Header codes like G92.0 cannot be reported on claims directly, they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at G92.0's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for G92.0 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Code First

  • underlying cause such as:
  • complications of immune effector cellular therapy (T80.82)

Code Also

  • , if applicable, associated signs and symptoms, such as:
  • cerebral edema (G93.6)
  • unspecified convulsions (R56.9)

Child Codes

Code Hierarchy

G92Toxic encephalopathyG92.0Immune effector cell-associated neurotoxicity syndrome
G92.0Immune effector cell-associated neurotoxicity syndrome

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