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G92.01 ICD-10-CM Code: Immune effector cell-associated neurotoxicity syndrome, grade 1

G92.01 is not a CMS-HCC payment code. MEAT criteria · RAF Calculator · HCC Buddy coding tools

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Code lookupG92.01

FY 2026 Apr update / Diseases of the nervous system (G00-G99) / Other disorders of the nervous system (G89-G99)

G92.01

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Immune effector cell-associated neurotoxicity syndrome, grade 1

A mild neurological side effect from immunotherapy treatment where the patient experiences minimal symptoms affecting brain function.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

Historical

Historical

Not used for CY2026 payment

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Inclusion Terms

Official
  • ICANS, grade 1

Excludes 2

Official
  • certain conditions originating in the perinatal period (P04-P96)Inherited from G00-G99
  • certain infectious and parasitic diseases (A00-B99)Inherited from G00-G99
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)Inherited from G00-G99
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)Inherited from G00-G99
  • endocrine, nutritional and metabolic diseases (E00-E88)Inherited from G00-G99
  • injury, poisoning and certain other consequences of external causes (S00-T88)Inherited from G00-G99
  • neoplasms (C00-D49)Inherited from G00-G99
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)Inherited from G00-G99

Includes

Official

No Includes notes are included in this display for G92.01. Check the code and parent instructions in the Code Book.

Excludes 1

Official

No Excludes 1 notes are included in this display for G92.01. Check the code and parent instructions in the Code Book.

Code First

Official
  • underlying cause such as:Inherited from G92.0
  • complications of immune effector cellular therapy (T80.82)Inherited from G92.0

Use Additional

Official

No Use Additional Code instructions are included in this display for G92.01. Check the code and parent instructions in the Code Book.

Code Also

Official
  • , if applicable, associated signs and symptoms, such as:Inherited from G92.0
  • cerebral edema (G93.6)Inherited from G92.0
  • unspecified convulsions (R56.9)Inherited from G92.0

Buddy Documentation Tip

HCC Buddy guidance
Ensure documentation clearly indicates Grade 1 severity to justify this specific code
Document the type of immunotherapy (CAR-T, checkpoint inhibitor, etc.) in the medical record

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is G92.01 an HCC code?

No. G92.01 is a billable ICD-10-CM code with no mapping under the current CMS-HCC V28 community payment model, and none under the ESRD, Part D RxHCC, or HHS-HCC models.

Code
G92.01
Description
Immune effector cell-associated neurotoxicity syndrome, grade 1
HCC (V28)
No CMS-HCC V28 mapping
RAF reference coefficient
Billable
Yes
Payment year
2026

Coder workflow notes

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What This Code Means

G92.01 is the ICD-10-CM diagnosis code for immune effector cell-associated neurotoxicity syndrome, grade 1. A mild neurological side effect from immunotherapy treatment where the patient experiences minimal symptoms affecting brain function. G92.01 sits in the ICD-10-CM chapter for diseases of the nervous system (g00-g99), within the section covering other disorders of the nervous system (g89-g99).

G92.01 is a billable ICD-10-CM code, but no current CMS-HCC V28 community payment mapping is shown, and none under the ESRD, Part D RxHCC, or HHS-HCC models. Do not assign risk adjustment value from this page when no source-backed mapping is shown; verify the applicable model and payment year.

Ensure documentation clearly indicates Grade 1 severity to justify this specific code.

HCC Buddy maintains structured V28 and V24 mapping, source-labeled coefficient references, and MEAT documentation criteria for G92.01 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Ensure documentation clearly indicates Grade 1 severity to justify this specific code
  • Document the type of immunotherapy (CAR-T, checkpoint inhibitor, etc.) in the medical record

Child Codes

Code Hierarchy

G92.01 code history

Code setChange
FY2022 (effective Oct 1, 2021)Added to the code set

Source: official CMS ICD-10-CM order and addenda files, FY2016 through FY2027.

Also searched as

  • G92 01
  • G9201

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