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G92.01 ICD-10-CM Code: Immune effector cell-associated neurotoxicity syndrome, grade 1

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FY 2026 Apr update / Diseases of the nervous system (G00-G99) / Other disorders of the nervous system (G89-G99)

G92.01

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Immune effector cell-associated neurotoxicity syndrome, grade 1

A mild neurological side effect from immunotherapy treatment where the patient experiences minimal symptoms affecting brain function.

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
G92Toxic encephalopathy
G92.0Immune effector cell-associated neurotoxicity syndrome
G92.01Immune effector cell-associated neurotoxicity syndrome, grade 1

Inclusion Terms

Official
  • ICANS, grade 1

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for G92.01 in this effective period.

Related Child Codes

Official
G92.00Immune effector cell-associated neurotoxicity syndrome, grade unspecified
G92.02Immune effector cell-associated neurotoxicity syndrome, grade 2
G92.03Immune effector cell-associated neurotoxicity syndrome, grade 3
G92.04Immune effector cell-associated neurotoxicity syndrome, grade 4
G92.05Immune effector cell-associated neurotoxicity syndrome, grade 5

Includes

Official

ICD-10-CM does not list Includes notes for G92.01 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for G92.01 in this effective period.

Code First

Official
  • underlying cause such as:
  • complications of immune effector cellular therapy (T80.82)

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for G92.01 in this effective period.

Code Also

Official
  • , if applicable, associated signs and symptoms, such as:
  • cerebral edema (G93.6)
  • unspecified convulsions (R56.9)

Buddy Documentation Tip

HCC Buddy guidance
Ensure documentation clearly indicates Grade 1 severity to justify this specific code
Document the type of immunotherapy (CAR-T, checkpoint inhibitor, etc.) in the medical record

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is G92.01 an HCC code?

No. G92.01 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

G92.01 is the ICD-10-CM diagnosis code for immune effector cell-associated neurotoxicity syndrome, grade 1. A mild neurological side effect from immunotherapy treatment where the patient experiences minimal symptoms affecting brain function. G92.01 sits in the ICD-10-CM chapter for diseases of the nervous system (g00-g99), within the section covering other disorders of the nervous system (g89-g99).

G92.01 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Ensure documentation clearly indicates Grade 1 severity to justify this specific code.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for G92.01 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Ensure documentation clearly indicates Grade 1 severity to justify this specific code
  • Document the type of immunotherapy (CAR-T, checkpoint inhibitor, etc.) in the medical record

Child Codes

Code Hierarchy

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