G92.00 ICD-10-CM Code: Immune effector cell-associated neurotoxicity syndrome, grade unspecified
HCC Buddy Code Card
Digital ICD-10 code-book layout with official code detail, always-visible risk models, Code Trumping, and Buddy coding guidance.
FY 2026 Apr update / Diseases of the nervous system (G00-G99) / Other disorders of the nervous system (G89-G99)
G92.00
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceImmune effector cell-associated neurotoxicity syndrome, grade unspecified
A serious neurological side effect that can occur after certain immunotherapy treatments (like CAR-T cell therapy), where the severity level has not been specified.
CMS-HCC V28
00
RAF 0
CMS-HCC V24
00
RAF 0
ACA/HHS
00
RAF 0
ESRD/PACE
00
RAF 0
RXHCC
00
RAF 0
Code Trumping
Basket needed
Code Book Path
Inclusion Terms
Official- ICANS, grade unspecified
Excludes 2
OfficialICD-10-CM does not list Excludes 2 notes for G92.00 in this effective period.
Related Child Codes
Includes
OfficialICD-10-CM does not list Includes notes for G92.00 in this effective period.
Excludes 1
OfficialICD-10-CM does not list Excludes 1 notes for G92.00 in this effective period.
Code First
Official- underlying cause such as:
- complications of immune effector cellular therapy (T80.82)
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for G92.00 in this effective period.
Code Also
Official- , if applicable, associated signs and symptoms, such as:
- cerebral edema (G93.6)
- unspecified convulsions (R56.9)
Buddy Documentation Tip
Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.
Is G92.00 an HCC code?
No. G92.00 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.
This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).
What This Code Means
G92.00 is the ICD-10-CM diagnosis code for immune effector cell-associated neurotoxicity syndrome, grade unspecified. A serious neurological side effect that can occur after certain immunotherapy treatments (like CAR-T cell therapy), where the severity level has not been specified. G92.00 sits in the ICD-10-CM chapter for diseases of the nervous system (g00-g99), within the section covering other disorders of the nervous system (g89-g99).
G92.00 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.
This code requires documentation of the grade/severity; if documented, use the specific grade code (G92.01-G92.05) instead.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for G92.00 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.