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E83.820 ICD-10-CM Code: Generalized arterial calcification of infancy with unspecified genetic causality

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FY 2026 Apr update / Endocrine, nutritional and metabolic diseases (E00-E89) / Metabolic disorders (E70-E88)

E83.820

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Generalized arterial calcification of infancy with unspecified genetic causality

This is a rare genetic condition where calcium deposits abnormally build up in arteries throughout the body during infancy, causing the arteries to harden and potentially affecting blood flow. The specific genetic cause has not been identified or documented in this case.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

HCC 28

Varies by metal level

ESRD/PACE

HCC 23

RAF 0.036

RXHCC

HCC 43

RAF 0.063

Code Book Path

Official
E83.8Other disorders of mineral metabolism
E83.82Disorders of pyrophosphate metabolism
E83.820Generalized arterial calcification of infancy with unspecified genetic causality

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for E83.820 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for E83.820 in this effective period.

Related Child Codes

Official
E83.821ENPP1 deficiency causing generalized arterial calcification of infancy
E83.822ENPP1 deficiency causing autosomal recessive hypophosphatemic rickets type 2
E83.823ABCC6 deficiency causing generalized arterial calcification of infancy
E83.824ABCC6 deficiency causing pseudoxanthoma elasticum
E83.825CD73 deficiency causing arterial calcification

Includes

Official

ICD-10-CM does not list Includes notes for E83.820 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for E83.820 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for E83.820 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for E83.820 in this effective period.

Code Also

Official
  • , if applicable, associated conditions such as:
  • heart failure (I50.-)
  • other secondary hypertension (I15.8)

Buddy Documentation Tip

HCC Buddy guidance
This code is used when GACI (generalized arterial calcification of infancy) is diagnosed but genetic testing has not identified the causative gene or results are inconclusive; if a specific genetic mutation is identified (such as ENPP1 or ABCC6), use the more specific code E83.821
Ensure documentation clearly states this is a generalized arterial calcification condition presenting in infancy and that genetic testing was either not performed or results were unspecified before assigning this code

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

Is E83.820 an HCC code?

E83.820 is not in the CMS-HCC V28 or V24 community payment model, but it does map to Other Significant Endocrine and Metabolic Disorders under the CMS-HCC ESRD model and Other Significant Endocrine and Metabolic Disorders under the Part D RxHCC model.

HCC Category Mapping

ESRDHCC 23, Other Significant Endocrine and Metabolic Disorders
0.036
RxHCCHCC 43, Other Significant Endocrine and Metabolic Disorders
0.063

Each model's RAF is its CMS base weight for that model's standard population, so weights are not directly comparable across models: CMS-HCC V28 and V24 use Community, Non-Dual, Aged; ESRD uses the dialysis continuing-enrollee model; RxHCC is the Part D continuing-enrollee, non-low-income, aged weight (a larger scale than CMS-HCC). ACA/HHS has no single weight — it varies by metal level. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.

Work E83.820 in the Code Book — tabular path, V28 RAF, and MEAT checklist →

MEAT Criteria for E83.820

For E83.820to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.

  • MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
  • EEvaluate: test results, medication response, or physical findings reviewed by the provider
  • AAssess: explicit mention in the assessment or plan with acknowledgment of status
  • TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis

Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed E83.820 during that encounter, not just copy-forwarded from a problem list.

Coder workflow notes

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What This Code Means

E83.820 is the ICD-10-CM diagnosis code for generalized arterial calcification of infancy with unspecified genetic causality. This is a rare genetic condition where calcium deposits abnormally build up in arteries throughout the body during infancy, causing the arteries to harden and potentially affecting blood flow. The specific genetic cause has not been identified or documented in this case. E83.820 sits in the ICD-10-CM chapter for endocrine, nutritional and metabolic diseases (e00-e89), within the section covering metabolic disorders (e70-e88).

E83.820 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

This code is used when GACI (generalized arterial calcification of infancy) is diagnosed but genetic testing has not identified the causative gene or results are inconclusive; if a specific genetic mutation is identified (such as ENPP1 or ABCC6), use the more specific code E83.821.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for E83.820 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • This code is used when GACI (generalized arterial calcification of infancy) is diagnosed but genetic testing has not identified the causative gene or results are inconclusive; if a specific genetic mutation is identified (such as ENPP1 or ABCC6), use the more specific code E83.821
  • Ensure documentation clearly states this is a generalized arterial calcification condition presenting in infancy and that genetic testing was either not performed or results were unspecified before assigning this code

Code Also

  • , if applicable, associated conditions such as:
  • heart failure (I50.-)
  • other secondary hypertension (I15.8)

Child Codes

Code Hierarchy

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