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Z15.05 ICD-10-CM Code: Genetic susceptibility to malignant neoplasm of fallopian tube(s)

ICD-10-CM Code View

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FY 2026 Apr update / Factors influencing health status and contact with health services (Z00-Z99) / Genetic carrier and genetic susceptibility to disease (Z14-Z15)

Z15.05

Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidance

Genetic susceptibility to malignant neoplasm of fallopian tube(s)

A person who has inherited genetic mutations that significantly increase their risk of developing cancer of the fallopian tubes.

CMS-HCC V28

N/A

Not mapped

CMS-HCC V24

N/A

Not mapped

ACA/HHS

N/A

Not mapped

ESRD/PACE

N/A

Not mapped

RXHCC

N/A

Not mapped

Code Book Path

Official
Z15Genetic susceptibility to disease
Z15.0Genetic susceptibility to malignant neoplasm
Z15.05Genetic susceptibility to malignant neoplasm of fallopian tube(s)

Inclusion Terms

Official

ICD-10-CM does not list inclusion terms for Z15.05 in this effective period.

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for Z15.05 in this effective period.

Related Child Codes

Official
Z15.01Genetic susceptibility to malignant neoplasm of breast
Z15.02Genetic susceptibility to malignant neoplasm of ovary
Z15.03Genetic susceptibility to malignant neoplasm of prostate
Z15.04Genetic susceptibility to malignant neoplasm of endometrium
Z15.06Genetic susceptibility to malignant neoplasm of digestive system

Includes

Official

ICD-10-CM does not list Includes notes for Z15.05 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for Z15.05 in this effective period.

Code First

Official
  • , if applicable, any current malignant neoplasm (C00-C75, C81-C96)

Use Additional

Official
  • code, if applicable, for any personal history of malignant neoplasm (Z85.-)

Code Also

Official

ICD-10-CM does not list Code Also instructions for Z15.05 in this effective period.

Buddy Documentation Tip

HCC Buddy guidance
Frequently associated with BRCA mutations, similar to ovarian cancer susceptibility
Document the specific genetic mutation identified in the patient's record

Current with CMS: FY2026 ICD-10-CM Apr 1 update (effective Apr 1 – Sep 30, 2026) · CMS-HCC V28, 100% phased in for payment year 2026. FY2027 code set already staged for October 1, 2026. How HCC Buddy stays current →

Is Z15.05 an HCC code?

No. Z15.05 is a billable ICD-10-CM code but does not map to any HCC category in V28, V24, ESRD, or RxHCC.

Code
Z15.05
Description
Genetic susceptibility to malignant neoplasm of fallopian tube(s)
HCC (V28)
No CMS-HCC V28 mapping
RAF
Billable
Yes
Payment year
2026

Coder workflow notes

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This code does not map to an HCC category in any model (V28, V24, ESRD, RxHCC).

What This Code Means

Z15.05 is the ICD-10-CM diagnosis code for genetic susceptibility to malignant neoplasm of fallopian tube(s). A person who has inherited genetic mutations that significantly increase their risk of developing cancer of the fallopian tubes. Z15.05 sits in the ICD-10-CM chapter for factors influencing health status and contact with health services (z00-z99), within the section covering genetic carrier and genetic susceptibility to disease (z14-z15).

Z15.05 is a billable ICD-10-CM code but does not map to a payment HCC under the CMS-HCC V28, V24, ESRD, or RxHCC risk adjustment models. It can be reported on Medicare Advantage encounter data submissions but it does not contribute to a beneficiary's RAF score and therefore does not affect risk-adjusted payments to the plan.

Frequently associated with BRCA mutations, similar to ovarian cancer susceptibility.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for Z15.05 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Coding Tips

  • Frequently associated with BRCA mutations, similar to ovarian cancer susceptibility
  • Document the specific genetic mutation identified in the patient's record

Child Codes

Code Hierarchy

Z15.05 code history

Code setChange
FY2026 (effective Oct 1, 2025)Added to the code set

Source: official CMS ICD-10-CM order and addenda files, FY2016 through FY2027.

Work Z15.05 in HCC Buddy

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