T41.42XA ICD-10-CM Code: Poisoning by unspecified anesthetic, intentional self-harm, initial encounter

T41.42XA is the ICD-10-CM diagnosis code for poisoning by unspecified anesthetic, intentional self-harm, initial encounter. T41.42XA sits in the ICD-10-CM chapter for injury, poisoning and certain other consequences of external causes (s00-t88), within the section covering poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (t36-t50).

Under the CMS-HCC V28 risk adjustment model, T41.42XA maps to Major Depression, Moderate or Severe, without Psychosis (HCC 155) with a community, non-dual, aged base RAF weight of 0.299. Under the older CMS-HCC V24 model, T41.42XA maps to Major Depressive, Bipolar, and Paranoid Disorders (HCC 59) with a community, non-dual, aged base RAF weight of 0.309. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.

Coders should report T41.42XA only when the provider documentation supports the specific condition described, since more specific codes within the same hierarchy can capture additional clinical detail and may carry a higher RAF weight. Because T41.42XA maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.