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T40.491 ICD-10-CM Code: Poisoning by other synthetic narcotics, accidental (unintentional)

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FY 2026 Apr update / Injury, poisoning and certain other consequences of external causes (S00-T88) / Poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (T36-T50)

T40.491

Header CodeICD-10-CMOfficial ICD-10-CMCodebook guidance

Poisoning by other synthetic narcotics, accidental (unintentional)

Poisoning by other synthetic narcotics, accidental (unintentional)

CMS-HCC V28

0

0

RAF 0

CMS-HCC V24

0

0

RAF 0

ACA/HHS

0

0

RAF 0

ESRD/PACE

0

0

RAF 0

RXHCC

0

0

RAF 0

Code Trumping

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Code Book Path

Official
T40.4Poisoning by, adverse effect of and underdosing of other synthetic narcotics
T40.49Poisoning by, adverse effect of and underdosing of other synthetic narcotics
T40.491Poisoning by other synthetic narcotics, accidental (unintentional)

Inclusion Terms

Official
  • Poisoning by other synthetic narcotics NOS

Excludes 2

Official

ICD-10-CM does not list Excludes 2 notes for T40.491 in this effective period.

Related Child Codes

Official
T40.491APoisoning by other synthetic narcotics, accidental (unintentional), initial encounter
T40.491DPoisoning by other synthetic narcotics, accidental (unintentional), subsequent encounter
T40.491SPoisoning by other synthetic narcotics, accidental (unintentional), sequela

Includes

Official

ICD-10-CM does not list Includes notes for T40.491 in this effective period.

Excludes 1

Official

ICD-10-CM does not list Excludes 1 notes for T40.491 in this effective period.

Code First

Official

ICD-10-CM does not list Code First sequencing instructions for T40.491 in this effective period.

Use Additional

Official

ICD-10-CM does not list Use Additional Code instructions for T40.491 in this effective period.

Code Also

Official

ICD-10-CM does not list Code Also instructions for T40.491 in this effective period.

Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.

What This Code Means

T40.491 is the ICD-10-CM diagnosis code for poisoning by other synthetic narcotics, accidental (unintentional). T40.491 sits in the ICD-10-CM chapter for injury, poisoning and certain other consequences of external causes (s00-t88), within the section covering poisoning by, adverse effects of and underdosing of drugs, medicaments and biological substances (t36-t50).

Header codes like T40.491 cannot be reported on claims directly, they organize child codes that share clinical context but the actual diagnosis must be coded to the highest level of specificity supported by the documentation. Coders should look at T40.491's child codes and select the one that matches the patient's documented presentation, since payers reject header codes submitted as the primary diagnosis. For risk adjustment workflows, header codes never contribute to a Medicare Advantage member's RAF score on their own; only billable child codes that happen to map to a payment HCC affect risk-adjusted plan payments.

HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for T40.491 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.

Child Codes

Code Hierarchy

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